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SKIL and RNF4
Data Source:
BioGRID
(two hybrid)
SKIL
RNF4
Description
SKI like proto-oncogene
ring finger protein 4
Image
GO Annotations
Cellular Component
Acrosomal Vesicle
Nucleus
Nucleoplasm
Transcription Regulator Complex
Protein-containing Complex
Nucleus
Nucleoplasm
Cytoplasm
Nuclear Body
PML Body
Microtubule End
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
Chromatin Binding
Protein Binding
SMAD Binding
DNA Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Transcription Factor Binding
Zinc Ion Binding
Nuclear Receptor Coactivator Activity
Nucleosome Binding
SUMO Polymer Binding
Identical Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Blastocyst Formation
Lymphocyte Homeostasis
Cell Cycle Arrest
Transforming Growth Factor Beta Receptor Signaling Pathway
Spermatogenesis
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of BMP Signaling Pathway
Response To Cytokine
Negative Regulation Of Cell Differentiation
Positive Regulation Of Axonogenesis
Lens Fiber Cell Differentiation
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Response To Arsenic-containing Substance
Protein Autoubiquitination
Protein K63-linked Ubiquitination
Protein K48-linked Ubiquitination
Protein K11-linked Ubiquitination
Protein K6-linked Ubiquitination
Regulation Of Spindle Assembly
Regulation Of Kinetochore Assembly
Pathways
Downregulation of SMAD2/3:SMAD4 transcriptional activity
Downregulation of SMAD2/3:SMAD4 transcriptional activity
Processing of DNA double-strand break ends
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Estimated glomerular filtration rate (
31152163
)
Glomerular filtration rate (creatinine) (
26831199
)
Glomerular filtration rate in non diabetics (creatinine) (
26831199
)
Prostate cancer (
21743467
)
Colorectal adenoma (advanced) (
29228715
)
Colorectal cancer (
29228715
)
Coronary artery calcified atherosclerotic plaque score in type 2 diabetes (
29221444
)
Dimensional psychopathology (Social) (
29496196
)
Tourette syndrome (
30818990
)
Interacting Genes
96 interacting genes:
ASCC3
CAMSAP1
CBX4
CDC16
CDC27
CHD3
CHPF
COL4A2
CPNE1
CPNE2
CPNE4
CXXC5
DEUP1
DHX30
DRG1
EEF1G
EIF4G2
ESR1
FAF1
FBLN1
FN1
FZR1
GAS8
GLUL
GOLGB1
HEY1
HEYL
HIPK1
HIPK3
HNRNPLL
IL36RN
KRT81
LRP1
MACF1
MORC4
MVP
MYG1
NCOR1
NCOR2
NEFL
NID1
NID2
NXF3
OIP5
PAPPA
PIAS1
PIAS3
PIAS4
PLCD3
PPL
PSG3
PSMC2
PTPRF
PYCR2
RNF4
RPS27
SASH1
SETDB1
SKI
SMAD1
SMAD2
SMAD3
SMAD4
SMUG1
SMURF2
SNRNP70
SNX17
SPARCL1
SRP72
STK16
SVEP1
TDG
TDP2
TFPI2
THAP5
THSD7A
TLE5
TPM2
TRAK1
TRIM62
TRIM69
TSKU
TTF2
UBE2I
UIMC1
USP25
VPS28
XPA
XRCC6
ZBTB3
ZBTB6
ZMYM2
ZMYM5
ZNF106
ZNF200
ZZEF1
133 interacting genes:
ACTB
AIM2
AKAP17A
AR
ARID3C
ATF2
ATXN1
BCL2L1
BTBD1
BTBD3
C14orf119
C18orf25
CAMK2B
CAMK2D
CCL2
CFL2
CREB1
DAXX
DDX39A
DDX39B
DES
DESI1
EHHADH
ESR1
ESRRA
FADD
FAM118A
FAM9A
FKBP6
GMCL1
GSC2
H3C14
HGS
HMGA1
HNF4A
HNRNPC
HNRNPCL1
HNRNPCL2
HNRNPH1
HNRNPK
IKBKG
IKZF1
IMPDH1
KLHL12
LCE1B
LCE1D
LCE1E
LCE1F
LCE2B
LCE2C
LCE2D
LCE3B
LCE5A
LXN
MYD88
NKX3-1
NMNAT1
NTAQ1
NVL
PAICS
PATZ1
PCBP3
PGR
PHC1
PROP1
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
RHOXF2
RUNX1T1
SCML2
SEPTIN3
SKIL
SNAPC5
SOX5
SP1
SRPK2
SSNA1
STX1A
STX2
STX4
SUMO1
SUMO2
TBP
TCF20
TERF2
TFG
THAP1
TRAF2
TRAF3
TRAF4
TRAF5
TRAIP
TRIM28
TRIM38
TRIM54
TRIP13
TRPS1
UBC
UBE2A
UBE2B
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2H
UBE2I
UBE2K
UBE2L6
UBE2N
UBE2T
UBE2W
UBQLN1
UBQLN2
UBTD2
UEVLD
VENTX
ZBTB26
ZBTB34
ZBTB6
ZC3H10
ZCCHC17
ZFP42
ZNF275
ZNF319
ZNF696
ZNF792
ZNRD2
Entrez ID
6498
6047
HPRD ID
01319
04167
Ensembl ID
ENSG00000136603
ENSG00000063978
Uniprot IDs
P12757
P78317
PDB IDs
3EQ5
5C4V
2EA6
2XEU
4PPE
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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