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SFPQ and LAMTOR5
Data Source:
BioGRID
(two hybrid)
SFPQ
LAMTOR5
Description
splicing factor proline and glutamine rich
late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
Image
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Nuclear Matrix
Nuclear Speck
Dendrite Cytoplasm
Paraspeckles
RNA Polymerase II Transcription Regulator Complex
Lysosome
Lysosomal Membrane
Cytosol
Protein-containing Complex
Ragulator Complex
Molecular Function
Transcription Regulatory Region Sequence-specific DNA Binding
Nucleic Acid Binding
DNA Binding
Chromatin Binding
RNA Binding
Protein Binding
Protein Homodimerization Activity
Histone Deacetylase Binding
Guanyl-nucleotide Exchange Factor Activity
Protein Binding
Molecular Adaptor Activity
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Alternative MRNA Splicing, Via Spliceosome
MRNA Splicing, Via Spliceosome
Double-strand Break Repair Via Homologous Recombination
Activation Of Innate Immune Response
Regulation Of Transcription, DNA-templated
MRNA Processing
RNA Splicing
Regulation Of Circadian Rhythm
Negative Regulation Of Circadian Rhythm
Innate Immune Response
Positive Regulation Of Sister Chromatid Cohesion
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Rhythmic Process
Histone H3 Deacetylation
Dendritic Transport Of Messenger Ribonucleoprotein Complex
Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Cell Cycle Arrest
Regulation Of Cell Size
Response To Virus
Positive Regulation Of Gene Expression
Regulation Of Macroautophagy
Viral Genome Replication
Positive Regulation Of TOR Signaling
Positive Regulation Of Interleukin-8 Production
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of NF-kappaB Transcription Factor Activity
Protein Localization To Lysosome
Cellular Response To Amino Acid Stimulus
Positive Regulation Of Protein Localization To Nucleus
Positive Regulation Of TORC1 Signaling
Positive Regulation Of RNA Polymerase II Regulatory Region Sequence-specific DNA Binding
Pathways
PTK6 Regulates Proteins Involved in RNA Processing
Suppression of apoptosis
Macroautophagy
MTOR signalling
mTORC1-mediated signalling
Energy dependent regulation of mTOR by LKB1-AMPK
TP53 Regulates Metabolic Genes
Regulation of PTEN gene transcription
Amino acids regulate mTORC1
Drugs
Copper
Artenimol
Diseases
GWAS
Allergic disease (asthma, hay fever or eczema) (
29083406
)
Endometrial cancer (
21499250
)
Hip circumference (
28552196
)
Interacting Genes
103 interacting genes:
APBB1
AR
CSNK2A1
ERG
ESR1
EXOSC5
FHL2
FUS
GAS7
H3-4
JPT1
LAMTOR5
LINC01554
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
NONO
PIN1
PPARG
PPP1CA
PRPF40A
PSPC1
PTBP1
RAC1
SIN3A
SMAD5
SNRPA
SREK1
TCERG1
TOP1
UBC
UBE2I
WBP4
ZMYM2
64 interacting genes:
ACAA2
AKR1C2
ALB
ANKRD46
ASGR1
BHMT
C9
CD74
CEP126
CEP70
CFB
CLIC5
DBI
DNAJA3
ECT2
EEF1A1
EIF3A
EIF4B
GAPDH
GIT1
GIT2
GPRASP1
HEBP2
HSPA9
ITGB1
KEAP1
KIF1B
KMT2E
LAMTOR4
LRIF1
MAF1
MCPH1
MED12L
MEOX2
MKLN1
MT2A
MYF6
MYH3
MYOG
NCOA6
PDK1
PEG10
PPARA
RABIF
RBP4
SERPINA1
SFPQ
SHB
SKP1
SMAD4
SNX5
TAF9
TBC1D4
TCAP
TCF12
TGFB1
TOP2B
TP53
TRIM55
TRIM63
UTP14A
YTHDC1
ZBTB16
ZNF592
Entrez ID
6421
10542
HPRD ID
07284
09773
Ensembl ID
ENSG00000116560
ENSG00000134248
Uniprot IDs
A0A384N5Z8
P23246
Q86VG2
A0A0C4DGV4
O43504
PDB IDs
4WII
4WIJ
4WIK
5WPA
6NCQ
6OWJ
3MS6
3MSH
5VOK
5X6U
5X6V
5Y38
5Y39
5Y3A
5YK3
6B9X
6EHP
6EHR
6NZD
6U62
6ULG
6WJ2
6WJ3
Enriched GO Terms of Interacting Partners
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