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LAMTOR5 and ZNF592
Data Source:
BioGRID
(two hybrid)
LAMTOR5
ZNF592
Description
late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
zinc finger protein 592
Image
No pdb structure
GO Annotations
Cellular Component
Lysosome
Lysosomal Membrane
Cytosol
Protein-containing Complex
Ragulator Complex
Nucleus
Molecular Function
Guanyl-nucleotide Exchange Factor Activity
Protein Binding
Molecular Adaptor Activity
DNA Binding
Protein Binding
Metal Ion Binding
Biological Process
Cell Cycle Arrest
Regulation Of Cell Size
Response To Virus
Positive Regulation Of Gene Expression
Regulation Of Macroautophagy
Viral Genome Replication
Positive Regulation Of TOR Signaling
Positive Regulation Of Interleukin-8 Production
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of NF-kappaB Transcription Factor Activity
Protein Localization To Lysosome
Cellular Response To Amino Acid Stimulus
Positive Regulation Of Protein Localization To Nucleus
Positive Regulation Of TORC1 Signaling
Positive Regulation Of RNA Polymerase II Regulatory Region Sequence-specific DNA Binding
Pathways
Macroautophagy
MTOR signalling
mTORC1-mediated signalling
Energy dependent regulation of mTOR by LKB1-AMPK
TP53 Regulates Metabolic Genes
Regulation of PTEN gene transcription
Amino acids regulate mTORC1
Drugs
Diseases
Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS
Alzheimer's disease (age of onset) (
22005931
)
Autism spectrum disorder or schizophrenia (
28540026
)
Bipolar disorder (
31043756
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Electrocardiographic traits (
32602732
)
Schizophrenia (
29483656
)
Interacting Genes
64 interacting genes:
ACAA2
AKR1C2
ALB
ANKRD46
ASGR1
BHMT
C9
CD74
CEP126
CEP70
CFB
CLIC5
DBI
DNAJA3
ECT2
EEF1A1
EIF3A
EIF4B
GAPDH
GIT1
GIT2
GPRASP1
HEBP2
HSPA9
ITGB1
KEAP1
KIF1B
KMT2E
LAMTOR4
LRIF1
MAF1
MCPH1
MED12L
MEOX2
MKLN1
MT2A
MYF6
MYH3
MYOG
NCOA6
PDK1
PEG10
PPARA
RABIF
RBP4
SERPINA1
SFPQ
SHB
SKP1
SMAD4
SNX5
TAF9
TBC1D4
TCAP
TCF12
TGFB1
TOP2B
TP53
TRIM55
TRIM63
UTP14A
YTHDC1
ZBTB16
ZNF592
4 interacting genes:
LAMTOR5
SMAD9
SRPK2
TCAF1
Entrez ID
10542
9640
HPRD ID
09773
10339
Ensembl ID
ENSG00000134248
ENSG00000166716
Uniprot IDs
A0A0C4DGV4
O43504
Q92610
PDB IDs
3MS6
3MSH
5VOK
5X6U
5X6V
5Y38
5Y39
5Y3A
5YK3
6B9X
6EHP
6EHR
6NZD
6U62
6ULG
6WJ2
6WJ3
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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