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RAB27A and LRIF1
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
RAB27A
LRIF1
Description
RAB27A, member RAS oncogene family
ligand dependent nuclear receptor interacting factor 1
Image
No pdb structure
GO Annotations
Cellular Component
Photoreceptor Outer Segment
Extracellular Region
Lysosome
Late Endosome
Golgi Apparatus
Cytosol
Apical Plasma Membrane
Secretory Granule
Dendrite
Secretory Granule Membrane
Multivesicular Body Membrane
Weibel-Palade Body
Melanosome Membrane
Specific Granule Lumen
Melanosome
Extracellular Exosome
Exocytic Vesicle
Chromosome, Telomeric Region
Barr Body
Nucleoplasm
Nuclear Matrix
Centriolar Satellite
Molecular Function
GTPase Activity
Protein Binding
GTP Binding
GDP Binding
Protein Domain Specific Binding
Myosin V Binding
Protein Binding
Retinoic Acid Receptor Binding
Biological Process
Protein Targeting
Exocytosis
Blood Coagulation
Positive Regulation Of Gene Expression
Antigen Processing And Presentation
Melanocyte Differentiation
Melanosome Localization
Melanosome Transport
Multivesicular Body Organization
Neutrophil Degranulation
Cytotoxic T Cell Degranulation
Natural Killer Cell Degranulation
Positive Regulation Of Exocytosis
Synaptic Vesicle Transport
Positive Regulation Of Phagocytosis
Multivesicular Body Sorting Pathway
Complement-dependent Cytotoxicity
Positive Regulation Of Regulated Secretory Pathway
Positive Regulation Of Reactive Oxygen Species Biosynthetic Process
Positive Regulation Of Constitutive Secretory Pathway
Exosomal Secretion
Regulation Of Transcription, DNA-templated
Dosage Compensation By Inactivation Of X Chromosome
Pathways
Insulin processing
Neutrophil degranulation
RAB geranylgeranylation
RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
Other phagocyte defects, including the following eight diseases: Chediak-Higashi syndrome; Griscelli syndrome, type 1 (GS1); Griscelli syndrome, type 2 (GS2); Griscelli syndrome, type 3 (GS3); beta-actin deficiency; Neutrophil-specific granule deficiency; Myeloperoxidase deficiency; Glucose 6-phosphate dehydrogenase deficiency; Shwachman syndrome
GWAS
Fractional exhaled nitric oxide levels (
25431337
)
Glioma (
30714141
)
Bone mineral content (
31790847
)
Intraocular pressure (
30591961
)
Interacting Genes
28 interacting genes:
ADRB2
APP
CEP126
COPS6
EEF1A1
ERG28
EXPH5
GDF9
GDI1
GZMB
LRIF1
MLPH
MYO5A
MYRIP
RABGGTB
RBM48
RIMS1
RIMS2
RPH3A
RPH3AL
STX1A
SYTL1
SYTL2
SYTL3
SYTL4
SYTL5
UNC13D
ZBTB16
144 interacting genes:
AKR1C3
ANKRD24
ANXA1
ANXA7
APLP1
ARL3
ATF3
ATP1B1
BANP
BARD1
BMI1
BOC
BRD7
BRMS1
CALR
CBX1
CBX3
CBX5
CCDC106
CDC42
CDKN1A
CDKN2C
CETN3
CHD3
CKMT2
COX17
CPE
CRACR2A
CRADD
CRCP
CRCT1
DDIT4
EIF6
ESR1
ETHE1
FAS
FEZ1
FHL2
FOSL2
FXR1
GADD45G
GC
GIT1
GPRASP2
GSTM4
H3-4
HAP1
HLA-DQA1
HMGB1
HMOX2
HSPB1
HSPB3
HSPBP1
HSPE1
ID2
IMMT
KAT5
KAT7
KBTBD7
KCNE3
KLHL20
KLK10
LAMA4
LAMTOR5
MAD2L1BP
MLLT3
MNAT1
MOB4
MPHOSPH6
MRPS12
MRPS6
NACA
NOC2L
NR3C1
NRBP1
NTAQ1
PAEP
PAFAH1B3
PCDHA4
PDCD5
PFDN1
PFN1
PIAS4
PIN1
PLEKHA4
PNP
POLR1C
POLR2C
POLR3F
PPARG
PQBP1
PRKAB2
PRKAR2A
PRMT1
PSG9
PSMD11
PSMD2
PSPC1
RAB27A
RAP1B
RARA
RBM5
RCC1
RFC5
RHOH
RIT1
RNF10
RORA
RPA2
RPL37A
RPLP1
RRM1
S100A8
SAT1
SELENBP1
SERPINB9
SETDB1
SMN1
SNRPN
SNU13
SPATA18
SPG7
STX5
SULT1E1
SUPT4H1
SUV39H2
TAF1D
TDGF1
TGIF1
THRB
TK1
TRBV2
TRDMT1
TSC22D1
TSEN15
TSPAN6
UBE2V2
UNC119
VIM
VPS26C
WDR62
WWC1
ZNF24
ZNF410
Entrez ID
5873
55791
HPRD ID
04845
17975
Ensembl ID
ENSG00000069974
ENSG00000121931
Uniprot IDs
A2RU94
P51159
Q5T3J3
PDB IDs
6HUF
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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