LRIF1 and CRCP

Data Source:
BioGRID (two hybrid)

		LRIF1	CRCP
Description		ligand dependent nuclear receptor interacting factor 1	CGRP receptor component
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Barr Body Nucleoplasm Nuclear Matrix Centriolar Satellite	Acrosomal Vesicle Nucleoplasm RNA Polymerase III Complex Cytosol Plasma Membrane DNA Polymerase III Complex
	Molecular Function	Protein Binding Retinoic Acid Receptor Binding	Nucleotide Binding Calcitonin Gene-related Peptide Receptor Activity DNA-directed 5'-3' RNA Polymerase Activity Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Dosage Compensation By Inactivation Of X Chromosome	Transcription By RNA Polymerase III Transcription Initiation From RNA Polymerase III Promoter Neuropeptide Signaling Pathway Positive Regulation Of Type I Interferon Production Innate Immune Response Defense Response To Virus
Pathways			Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases
GWAS		Bone mineral content ( 31790847) Intraocular pressure ( 30591961)	Aortic root size ( 21223598) Estimated glomerular filtration rate ( 31152163)
Interacting Genes		144 interacting genes: AKR1C3 ANKRD24 ANXA1 ANXA7 APLP1 ARL3 ATF3 ATP1B1 BANP BARD1 BMI1 BOC BRD7 BRMS1 CALR CBX1 CBX3 CBX5 CCDC106 CDC42 CDKN1A CDKN2C CETN3 CHD3 CKMT2 COX17 CPE CRACR2A CRADD CRCP CRCT1 DDIT4 EIF6 ESR1 ETHE1 FAS FEZ1 FHL2 FOSL2 FXR1 GADD45G GC GIT1 GPRASP2 GSTM4 H3-4 HAP1 HLA-DQA1 HMGB1 HMOX2 HSPB1 HSPB3 HSPBP1 HSPE1 ID2 IMMT KAT5 KAT7 KBTBD7 KCNE3 KLHL20 KLK10 LAMA4 LAMTOR5 MAD2L1BP MLLT3 MNAT1 MOB4 MPHOSPH6 MRPS12 MRPS6 NACA NOC2L NR3C1 NRBP1 NTAQ1 PAEP PAFAH1B3 PCDHA4 PDCD5 PFDN1 PFN1 PIAS4 PIN1 PLEKHA4 PNP POLR1C POLR2C POLR3F PPARG PQBP1 PRKAB2 PRKAR2A PRMT1 PSG9 PSMD11 PSMD2 PSPC1 RAB27A RAP1B RARA RBM5 RCC1 RFC5 RHOH RIT1 RNF10 RORA RPA2 RPL37A RPLP1 RRM1 S100A8 SAT1 SELENBP1 SERPINB9 SETDB1 SMN1 SNRPN SNU13 SPATA18 SPG7 STX5 SULT1E1 SUPT4H1 SUV39H2 TAF1D TDGF1 TGIF1 THRB TK1 TRBV2 TRDMT1 TSC22D1 TSEN15 TSPAN6 UBE2V2 UNC119 VIM VPS26C WDR62 WWC1 ZNF24 ZNF410	9 interacting genes: AGR2 CALCRL DYNLRB1 GSC2 LRIF1 POLR3H TCF12 VAV2 ZMIZ2
Entrez ID		55791	27297
HPRD ID		17975	12089
Ensembl ID		ENSG00000121931	ENSG00000241258
Uniprot IDs		Q5T3J3	A0A024RDL0 O75575
PDB IDs
Enriched GO Terms of Interacting Partners?
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