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LRIF1 and PIAS4
Data Source:
BioGRID
(two hybrid)
LRIF1
PIAS4
Description
ligand dependent nuclear receptor interacting factor 1
protein inhibitor of activated STAT 4
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Chromosome, Telomeric Region
Barr Body
Nucleoplasm
Nuclear Matrix
Centriolar Satellite
Nucleus
Nucleoplasm
Cytoplasm
Nuclear Matrix
PML Body
Transferase Complex
Molecular Function
Protein Binding
Retinoic Acid Receptor Binding
RNA Polymerase II Transcription Factor Binding
DNA Binding
Transcription Coregulator Activity
Transcription Corepressor Activity
Protein Binding
Protein C-terminus Binding
Zinc Ion Binding
SUMO Transferase Activity
Ubiquitin Protein Ligase Binding
SUMO Ligase Activity
Biological Process
Regulation Of Transcription, DNA-templated
Dosage Compensation By Inactivation Of X Chromosome
Negative Regulation Of Transcription By RNA Polymerase II
Double-strand Break Repair Via Nonhomologous End Joining
Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Wnt Signaling Pathway
Protein Sumoylation
Negative Regulation Of NF-kappaB Transcription Factor Activity
Positive Regulation Of Protein Sumoylation
Vitamin D Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Keratinocyte Apoptotic Process
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Pathways
Vitamin D (calciferol) metabolism
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription factors
SUMOylation of ubiquitinylation proteins
SUMOylation of transcription cofactors
SUMOylation of SUMOylation proteins
SUMOylation of intracellular receptors
SUMOylation of intracellular receptors
SUMOylation of DNA replication proteins
SUMOylation of immune response proteins
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Nonhomologous End-Joining (NHEJ)
Processing of DNA double-strand break ends
G2/M DNA damage checkpoint
Drugs
Diseases
GWAS
Bone mineral content (
31790847
)
Intraocular pressure (
30591961
)
Chronic lymphocytic leukemia (
28165464
)
HDL cholesterol levels (
32203549
)
Refractive error (
32231278
)
Interacting Genes
144 interacting genes:
AKR1C3
ANKRD24
ANXA1
ANXA7
APLP1
ARL3
ATF3
ATP1B1
BANP
BARD1
BMI1
BOC
BRD7
BRMS1
CALR
CBX1
CBX3
CBX5
CCDC106
CDC42
CDKN1A
CDKN2C
CETN3
CHD3
CKMT2
COX17
CPE
CRACR2A
CRADD
CRCP
CRCT1
DDIT4
EIF6
ESR1
ETHE1
FAS
FEZ1
FHL2
FOSL2
FXR1
GADD45G
GC
GIT1
GPRASP2
GSTM4
H3-4
HAP1
HLA-DQA1
HMGB1
HMOX2
HSPB1
HSPB3
HSPBP1
HSPE1
ID2
IMMT
KAT5
KAT7
KBTBD7
KCNE3
KLHL20
KLK10
LAMA4
LAMTOR5
MAD2L1BP
MLLT3
MNAT1
MOB4
MPHOSPH6
MRPS12
MRPS6
NACA
NOC2L
NR3C1
NRBP1
NTAQ1
PAEP
PAFAH1B3
PCDHA4
PDCD5
PFDN1
PFN1
PIAS4
PIN1
PLEKHA4
PNP
POLR1C
POLR2C
POLR3F
PPARG
PQBP1
PRKAB2
PRKAR2A
PRMT1
PSG9
PSMD11
PSMD2
PSPC1
RAB27A
RAP1B
RARA
RBM5
RCC1
RFC5
RHOH
RIT1
RNF10
RORA
RPA2
RPL37A
RPLP1
RRM1
S100A8
SAT1
SELENBP1
SERPINB9
SETDB1
SMN1
SNRPN
SNU13
SPATA18
SPG7
STX5
SULT1E1
SUPT4H1
SUV39H2
TAF1D
TDGF1
TGIF1
THRB
TK1
TRBV2
TRDMT1
TSC22D1
TSEN15
TSPAN6
UBE2V2
UNC119
VIM
VPS26C
WDR62
WWC1
ZNF24
ZNF410
85 interacting genes:
ACTN1
ALDOA
AR
AREL1
BARD1
BRCA1
BTAF1
CALCOCO2
CEBPD
CHD3
CLK1
COIL
ESRRA
FTH1
GADD45G
HDAC1
HDAC2
HNF4A
HNRNPUL1
HTT
IL15RA
IMMT
IMPDH2
IRF3
IRF7
KNTC1
KPNB1
KRT18
LAMP2
LCE1D
LEF1
LRIF1
MAGEH1
MAP1LC3A
MDC1
MPRIP
NEFL
NR4A2
OAZ1
OPTN
PARP1
PDE4A
PDE4D
PDE4DIP
PHF11
PHGDH
PIAS1
PIAS2
PLAG1
PRKCZ
PRPF40A
PTN
RIF1
SATB1
SERBP1
SERPINA5
SETDB1
SH3GL3
SKIL
SMAD1
SMAD2
SMAD3
SMAD4
SMAD7
SNAI2
SNIP1
SUMO1
SUMO2
SUMO3
TADA3
TCERG1
TICAM1
TOP2A
TP53
TRIM27
TRIM32
TRIM38
UBE2I
UBE2K
VHL
VIM
ZBTB34
ZHX1
ZNF512B
ZW10
Entrez ID
55791
51588
HPRD ID
17975
06910
Ensembl ID
ENSG00000121931
ENSG00000105229
Uniprot IDs
Q5T3J3
B3KMR4
Q8N2W9
PDB IDs
Enriched GO Terms of Interacting Partners
?
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Tagcloud (Difference)
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Tagcloud (Intersection)
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