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PTPN9 and TMX2
Data Source:
BioGRID
(two hybrid)
PTPN9
TMX2
Description
protein tyrosine phosphatase non-receptor type 9
thioredoxin related transmembrane protein 2
Image
GO Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Neuron Projection Terminus
Mitochondrion
Endoplasmic Reticulum Membrane
Integral Component Of Membrane
Mitochondrial Membrane
Membrane-bounded Organelle
Mitochondria-associated Endoplasmic Reticulum Membrane
Molecular Function
Protein Tyrosine Phosphatase Activity
Non-membrane Spanning Protein Tyrosine Phosphatase Activity
Protein Binding
Protein Binding
Disulfide Oxidoreductase Activity
Identical Protein Binding
Biological Process
Protein Dephosphorylation
Negative Regulation Of Neuron Projection Development
Peptidyl-tyrosine Dephosphorylation
Cellular Response To Cytokine Stimulus
Positive Regulation Of Protein Localization To Plasma Membrane
Brain Development
Pathways
Interleukin-37 signaling
Drugs
Diseases
GWAS
Estimated glomerular filtration rate (
31015462
)
Height (
25429064
31562340
20189936
)
Type 2 diabetes (
30297969
)
Autism spectrum disorder or schizophrenia (
28540026
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Neuroticism (
29255261
)
Problematic alcohol use (
32451486
)
Reticulocyte count (
32888494
)
Schizophrenia (
25056061
29483656
)
Interacting Genes
46 interacting genes:
AGTRAP
AQP6
ARL13B
ARL6IP1
ATP5PF
BSND
CCR2
CDR1
CERS4
CMTM4
CMTM5
COQ3
CPLX4
CREB3
CREB3L1
DERL2
EBP
FAM114A2
FKBP7
GET1
GHR
GJB1
GORAB
HSD17B11
HSD17B13
LIME1
LMNA
MAL2
NSF
PBX3
PEX12
PLIN3
REEP6
RTN3
SCAMP1
SLC16A13
SLC30A8
SLC7A1
SPAG4
STX6
SYP
TMCO2
TMEM80
TMEM86B
TMX2
YIF1A
164 interacting genes:
AGPAT3
AGPAT4
AGPAT5
AIG1
AQP6
ARV1
ASGR1
ASPH
ATXN1
BDKRB1
BET1
BNIP1
BNIP2
BNIP3
BRICD5
BTN2A2
C2CD2L
C3orf52
CCDC167
CCL2
CD81
CDIPT
CDS2
CMTM7
COL8A2
COMMD8
COX20
CTSA
CTXN3
CXCL16
CXorf66
CYBC1
CYP4F2
DERL1
DGAT2L6
EMD
EMP3
F2RL1
FA2H
FAM177A1
FAM241B
FAM3C
FAXDC2
FDFT1
FUNDC2
FXYD6-FXYD2
GIMAP1
GIMAP5
GJB2
HACD2
HHATL
HMOX2
HSD17B11
HSD17B13
HSD3B7
HTATIP2
IER3
IER3IP1
IGFBP5
INSIG2
ITGAM
LEPROT
LEPROTL1
LHFPL5
LRAT
MALL
MFF
MFSD14B
MGLL
MGST3
MIP
MLN
MS4A1
MTNR1A
NAT8
NDUFA3
NINJ2
NRM
NSDHL
NSG1
ORMDL2
OTULINL
PAEP
PEDS1-UBE2V1
PEX16
PKMYT1
PLP2
PNLIPRP1
PRAF2
PRB1
PTAFR
PTPN9
RABAC1
REEP2
REEP4
RFT1
RNF24
RTP2
RUSF1
SACM1L
SCAMP5
SCD
SELENOK
SERF1A
SERF1B
SERP2
SFT2D1
SFXN1
SFXN3
SLC22A18
SLC22A2
SLC29A2
SLC35A1
SMAGP
SMCO4
SMIM1
STATH
STX12
STX3
STX7
THBD
THSD7B
TMBIM6
TMEM115
TMEM120A
TMEM120B
TMEM121
TMEM128
TMEM140
TMEM14B
TMEM14C
TMEM176A
TMEM201
TMEM203
TMEM208
TMEM222
TMEM239
TMEM254
TMEM31
TMEM50B
TMEM51
TMEM65
TMEM71
TMEM86B
TMEM97
TPRG1
TRAM1L1
TREX1
TSNARE1
TSPAN2
TVP23B
UBE2J1
UNC93A
VAMP1
VAMP3
VAMP4
VAMP5
VAPA
VAPB
WFDC2
YIF1A
YIPF1
YIPF2
YIPF6
Entrez ID
5780
51075
HPRD ID
02864
07159
Ensembl ID
ENSG00000169410
ENSG00000213593
Uniprot IDs
P43378
Q6IQ43
Q9Y320
PDB IDs
2PA5
4GE2
4GE5
4GE6
4ICZ
6KZQ
6L03
2DJ0
Enriched GO Terms of Interacting Partners
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