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SAR1A and TTPA
Data Source:
BioGRID
(two hybrid)
SAR1A
TTPA
Description
secretion associated Ras related GTPase 1A
alpha tocopherol transfer protein
Image
GO Annotations
Cellular Component
Golgi Membrane
COPII Vesicle Coat
Endoplasmic Reticulum Exit Site
Late Endosome
Cytosol
Molecular Function
GTPase Activity
Protein Binding
GTP Binding
Protein Binding
Phosphatidylinositol-4,5-bisphosphate Binding
Vitamin E Binding
Phosphatidylinositol-3,4-bisphosphate Binding
Lipid Transfer Activity
Phosphatidylinositol Bisphosphate Binding
Biological Process
Regulation Of COPII Vesicle Coating
Intracellular Protein Transport
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Vesicle Organization
Membrane Organization
Positive Regulation Of Protein Exit From Endoplasmic Reticulum
COPII-coated Vesicle Cargo Loading
Lipid Metabolic Process
Response To Nutrient
Response To PH
Developmental Process
Vitamin E Metabolic Process
Vitamin Transport
Intracellular PH Reduction
Negative Regulation Of Cell Death
Intermembrane Lipid Transfer
Pathways
Vitamin E
Drugs
Diseases
Ataxia with isolated vitamin E deficiency (AVED); Friedreich-like ataxia
GWAS
Interacting Genes
69 interacting genes:
ADGRE2
AIG1
ALG8
APP
AQP1
AQP10
AQP3
ASGR1
ATXN1
BCL2L2
C14orf180
C3orf52
CD53
CD81
CES1
CLDN19
CLDND2
CLEC7A
CMTM5
COL4A5
CTSA
CXCL16
EMP3
ERG28
FAM3C
GJB2
GOLT1B
GRM2
GYPA
HMOX2
JAGN1
LAT
LHFPL5
MARCHF5
MIP
MOSPD3
NAT8
NRM
ORMDL1
PLLP
PLN
PLP2
RHOT2
RMDN2
SEC22A
SERP1
SLC35A1
SMIM1
SNAP47
STX7
STX8
TMEM107
TMEM109
TMEM187
TMEM218
TMEM243
TMEM254
TMEM267
TMEM42
TMEM97
TRAF3
TRAM1L1
TTPA
UBIAD1
UNC50
UPK1B
VAMP3
VAMP4
VAMP5
46 interacting genes:
AGTRAP
APOA5
APOC2
APP
ARFIP2
ARMC12
BIRC7
CISD2
CMTM4
CMTM5
COQ3
CYSRT1
DGAT2L6
DHODH
FADS6
FAM114A2
FAM25A
FAM25C
FAM25G
FGF14
FKBP7
GOLGA2
HSD17B11
JOSD2
KRTAP10-7
KRTAP12-2
KRTAP12-3
KRTAP2-3
KRTAP2-4
LEUTX
MAL2
MRM1
NBPF19
NDUFA7
NOTCH2NLA
PEX12
REEP2
RPRM
SAR1A
SCAMP1
SCAMP5
SDR16C5
SLC35E3
SYNGR3
THAP4
TPD52
Entrez ID
56681
7274
HPRD ID
07608
02685
Ensembl ID
ENSG00000079332
ENSG00000137561
Uniprot IDs
Q5SQT9
Q9NR31
P49638
PDB IDs
2GAO
1OIP
1OIZ
1R5L
5MUE
5MUG
Enriched GO Terms of Interacting Partners
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