SAR1A and TMEM109

Data Source:
BioGRID (two hybrid)

		SAR1A	TMEM109
Description		secretion associated Ras related GTPase 1A	transmembrane protein 109
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane COPII Vesicle Coat Endoplasmic Reticulum Exit Site	Nuclear Outer Membrane Integral Component Of Membrane Sarcoplasmic Reticulum Membrane Extracellular Exosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding	Molecular_function Voltage-gated Ion Channel Activity Protein Binding
	Biological Process	Regulation Of COPII Vesicle Coating Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Organization Membrane Organization Positive Regulation Of Protein Exit From Endoplasmic Reticulum COPII-coated Vesicle Cargo Loading	Ion Transmembrane Transport Regulation Of Ion Transmembrane Transport Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Cell Death Cellular Response To Gamma Radiation
Pathways
Drugs
Diseases
GWAS
Interacting Genes		69 interacting genes: ADGRE2 AIG1 ALG8 APP AQP1 AQP10 AQP3 ASGR1 ATXN1 BCL2L2 C14orf180 C3orf52 CD53 CD81 CES1 CLDN19 CLDND2 CLEC7A CMTM5 COL4A5 CTSA CXCL16 EMP3 ERG28 FAM3C GJB2 GOLT1B GRM2 GYPA HMOX2 JAGN1 LAT LHFPL5 MARCHF5 MIP MOSPD3 NAT8 NRM ORMDL1 PLLP PLN PLP2 RHOT2 RMDN2 SEC22A SERP1 SLC35A1 SMIM1 SNAP47 STX7 STX8 TMEM107 TMEM109 TMEM187 TMEM218 TMEM243 TMEM254 TMEM267 TMEM42 TMEM97 TRAF3 TRAM1L1 TTPA UBIAD1 UNC50 UPK1B VAMP3 VAMP4 VAMP5	16 interacting genes: AQP2 AQP9 ERGIC3 GOLM1 GPX8 LMNA MGST3 MTIF3 PDZK1IP1 RNF170 SAR1A SLC18A2 SPINT1 STOM TMEM52B TMEM80
Entrez ID		56681	79073
HPRD ID		07608	14687
Ensembl ID		ENSG00000079332	ENSG00000110108
Uniprot IDs		Q5SQT9 Q9NR31	Q9BVC6
PDB IDs		2GAO
Enriched GO Terms of Interacting Partners?
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