SAR1A and TRAM1L1

Data Source:
BioGRID (two hybrid)

		SAR1A	TRAM1L1
Description		secretion associated Ras related GTPase 1A	translocation associated membrane protein 1 like 1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane COPII Vesicle Coat Endoplasmic Reticulum Exit Site	Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding	Protein Binding
	Biological Process	Regulation Of COPII Vesicle Coating Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Organization Membrane Organization Positive Regulation Of Protein Exit From Endoplasmic Reticulum COPII-coated Vesicle Cargo Loading	SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation Protein Insertion Into ER Membrane
Pathways
Drugs
Diseases
GWAS			Bronchopulmonary dysplasia ( 23897914) Lateral ventricle volume in trauma-exposed individuals ( 29187748) Metabolite levels ( 23823483) Obesity (extreme) ( 19553259) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Visceral adipose tissue adjusted for BMI ( 22589738)
Interacting Genes		69 interacting genes: ADGRE2 AIG1 ALG8 APP AQP1 AQP10 AQP3 ASGR1 ATXN1 BCL2L2 C14orf180 C3orf52 CD53 CD81 CES1 CLDN19 CLDND2 CLEC7A CMTM5 COL4A5 CTSA CXCL16 EMP3 ERG28 FAM3C GJB2 GOLT1B GRM2 GYPA HMOX2 JAGN1 LAT LHFPL5 MARCHF5 MIP MOSPD3 NAT8 NRM ORMDL1 PLLP PLN PLP2 RHOT2 RMDN2 SEC22A SERP1 SLC35A1 SMIM1 SNAP47 STX7 STX8 TMEM107 TMEM109 TMEM187 TMEM218 TMEM243 TMEM254 TMEM267 TMEM42 TMEM97 TRAF3 TRAM1L1 TTPA UBIAD1 UNC50 UPK1B VAMP3 VAMP4 VAMP5	29 interacting genes: ASGR2 BDKRB1 BSCL2 CD53 CD79A CD99L2 CLEC1A CLSTN3 CREB3 CREB3L1 CYBC1 ERGIC3 EVI2B FAM209A FKBP7 GPX8 HTR2B LMNA LRRC59 MFF MUC1 PLEKHF2 PLEKHO1 PLPP2 SAR1A TMED8 TMEM52B TMEM79 TMX2
Entrez ID		56681	133022
HPRD ID		07608	11643
Ensembl ID		ENSG00000079332	ENSG00000174599
Uniprot IDs		Q5SQT9 Q9NR31	Q8N609
PDB IDs		2GAO
Enriched GO Terms of Interacting Partners?
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