TTPA and SYNGR3

Data Source:
BioGRID (two hybrid)

		TTPA	SYNGR3
Description		alpha tocopherol transfer protein	synaptogyrin 3
Image			No pdb structure
GO Annotations	Cellular Component	Late Endosome Cytosol	Synaptic Vesicle Integral Component Of Membrane Synaptic Vesicle Membrane Neuromuscular Junction
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Vitamin E Binding Phosphatidylinositol-3,4-bisphosphate Binding Lipid Transfer Activity Phosphatidylinositol Bisphosphate Binding	Protein Binding
	Biological Process	Lipid Metabolic Process Response To Nutrient Response To PH Developmental Process Vitamin E Metabolic Process Vitamin Transport Intracellular PH Reduction Negative Regulation Of Cell Death Intermembrane Lipid Transfer	Substantia Nigra Development Positive Regulation Of Transporter Activity Regulated Exocytosis
Pathways		Vitamin E
Drugs
Diseases		Ataxia with isolated vitamin E deficiency (AVED); Friedreich-like ataxia
GWAS
Interacting Genes		46 interacting genes: AGTRAP APOA5 APOC2 APP ARFIP2 ARMC12 BIRC7 CISD2 CMTM4 CMTM5 COQ3 CYSRT1 DGAT2L6 DHODH FADS6 FAM114A2 FAM25A FAM25C FAM25G FGF14 FKBP7 GOLGA2 HSD17B11 JOSD2 KRTAP10-7 KRTAP12-2 KRTAP12-3 KRTAP2-3 KRTAP2-4 LEUTX MAL2 MRM1 NBPF19 NDUFA7 NOTCH2NLA PEX12 REEP2 RPRM SAR1A SCAMP1 SCAMP5 SDR16C5 SLC35E3 SYNGR3 THAP4 TPD52	14 interacting genes: ACSF2 ARFIP1 EHHADH GAD2 GLP1R HSBP1L1 MIDN MPP1 NDRG4 PLIN3 PNKP SH3GLB1 SPG21 TTPA
Entrez ID		7274	9143
HPRD ID		02685	06801
Ensembl ID		ENSG00000137561	ENSG00000127561
Uniprot IDs		P49638	O43761
PDB IDs		1OIP 1OIZ 1R5L 5MUE 5MUG
Enriched GO Terms of Interacting Partners?
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