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SAR1A and COL4A5
Data Source:
BioGRID
(two hybrid)
SAR1A
COL4A5
Description
secretion associated Ras related GTPase 1A
collagen type IV alpha 5 chain
Image
GO Annotations
Cellular Component
Golgi Membrane
COPII Vesicle Coat
Endoplasmic Reticulum Exit Site
Extracellular Region
Collagen Type IV Trimer
Basement Membrane
Extracellular Space
Endoplasmic Reticulum Lumen
Extracellular Matrix
Neuromuscular Junction
Collagen-containing Extracellular Matrix
Molecular Function
GTPase Activity
Protein Binding
GTP Binding
Extracellular Matrix Structural Constituent
Extracellular Matrix Structural Constituent Conferring Tensile Strength
Biological Process
Regulation Of COPII Vesicle Coating
Intracellular Protein Transport
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Vesicle Organization
Membrane Organization
Positive Regulation Of Protein Exit From Endoplasmic Reticulum
COPII-coated Vesicle Cargo Loading
Neuromuscular Junction Development
Extracellular Matrix Organization
Collagen-activated Tyrosine Kinase Receptor Signaling Pathway
Pathways
Collagen degradation
Collagen degradation
Extracellular matrix organization
Collagen biosynthesis and modifying enzymes
Signaling by PDGF
Assembly of collagen fibrils and other multimeric structures
Integrin cell surface interactions
Integrin cell surface interactions
Anchoring fibril formation
Crosslinking of collagen fibrils
Laminin interactions
Laminin interactions
Non-integrin membrane-ECM interactions
ECM proteoglycans
NCAM1 interactions
Collagen chain trimerization
Regulation of expression of SLITs and ROBOs
Drugs
Diseases
Alport syndrome
GWAS
Interacting Genes
69 interacting genes:
ADGRE2
AIG1
ALG8
APP
AQP1
AQP10
AQP3
ASGR1
ATXN1
BCL2L2
C14orf180
C3orf52
CD53
CD81
CES1
CLDN19
CLDND2
CLEC7A
CMTM5
COL4A5
CTSA
CXCL16
EMP3
ERG28
FAM3C
GJB2
GOLT1B
GRM2
GYPA
HMOX2
JAGN1
LAT
LHFPL5
MARCHF5
MIP
MOSPD3
NAT8
NRM
ORMDL1
PLLP
PLN
PLP2
RHOT2
RMDN2
SEC22A
SERP1
SLC35A1
SMIM1
SNAP47
STX7
STX8
TMEM107
TMEM109
TMEM187
TMEM218
TMEM243
TMEM254
TMEM267
TMEM42
TMEM97
TRAF3
TRAM1L1
TTPA
UBIAD1
UNC50
UPK1B
VAMP3
VAMP4
VAMP5
46 interacting genes:
ABHD4
ANTXR2
ANXA7
APP
ATP6V0B
BSND
CD53
CD79A
CD93
CDKN1A
CERS4
CLDN7
DAZAP2
DCN
ELOVL4
ERGIC3
FAM209A
FBLN2
FFAR2
FN1
GPX8
HABP2
KCNJ6
MATN2
MFF
MMP9
MTIF3
NCR3LG1
NEMP1
NR1H2
OSM
RELL2
RNF10
SAR1A
SERPINE2
SLC10A4
SLC10A6
SLC16A2
SLC18A1
SLC35C2
SLC39A2
SMN1
THAP4
TK1
TMEM80
TSPO2
Entrez ID
56681
1287
HPRD ID
07608
02363
Ensembl ID
ENSG00000079332
ENSG00000188153
Uniprot IDs
Q5SQT9
Q9NR31
A7MBN3
P29400
Q49AM6
PDB IDs
2GAO
5NAZ
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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