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PROP1 and POU6F2
Data Source:
BioGRID
(two hybrid)
PROP1
POU6F2
Description
PROP paired-like homeobox 1
POU class 6 homeobox 2
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Transcription Regulator Complex
Chromatin
Nucleus
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Protein Binding
Sequence-specific Double-stranded DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Protein Binding
Biological Process
Regulation Of Transcription By RNA Polymerase II
Central Nervous System Development
Pituitary Gland Development
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Ganglion Mother Cell Fate Determination
Central Nervous System Development
Visual Perception
Pathways
Drugs
Diseases
Pituitary Dwarfism (PD); Isolated growth hormone deficiency (IGHD); Short Stature and Pituitary Defects (SSPD); Insulin-like growth factor 1 deficiency (IGFD)
GWAS
Adult body size (
32376654
)
Attention deficit hyperactivity disorder (inattention symptoms) (
32595297
)
Feeling hurt (
29500382
)
Glaucoma (multi-trait analysis) (
31959993
)
Hand grip strength (
29691431
)
Intraocular pressure (
29785010
31959993
30054594
)
Motion sickness (
25628336
)
Refractive error (
32231278
)
Tea consumption (
31046077
)
Interacting Genes
54 interacting genes:
ABHD11
ARSA
BATF2
C11orf1
C19orf54
C1orf94
C6orf15
C9orf24
COX6B2
CRYBA1
CYSRT1
DAZAP2
EFEMP2
FAM166A
FAM168A
HDHD3
HESX1
HNRNPF
HOXA1
INTS11
KHDC1
KRTAP13-1
KRTAP19-1
KRTAP19-6
KRTAP19-7
KRTAP6-3
KRTAP8-1
MAGED1
METTL15
METTL27
NR1D2
OLIG3
OXER1
P4HA3
PITX2
PLEKHB2
POU6F2
PSMB11
PSMB4
RNF144B
RNF4
SMUG1
SUMO1
TBX22
TEKT4
TEKT5
TENT5B
TINAGL1
TLE5
TMEM42
TRIM42
UBE2I
UFSP1
ZNF503
143 interacting genes:
ACTN3
ANKRD10
ARHGEF6
ASB13
BANP
BFSP2
BHLHE40
C1orf109
C5
CCHCR1
CCNC
CCNK
CDC23
CDC37
CDKN2C
CHAF1A
CIB3
CINP
CSNK2A1
CSTF2
CTNNA3
DDX6
DTNB
DYDC1
EBF1
EIF3F
EIF4EBP1
EPHB6
FHL2
FNDC3B
FOSB
GCM2
GLIS2
GMEB2
GOLGA6L9
HGS
HIVEP1
HNF1B
HOXC5
HOXC8
HSPA4
IGFN1
IMPDH2
IQUB
IRX4
ISX
KDF1
KIF5B
KLHL11
KPNA5
KPNA6
KRTAP8-1
L3MBTL2
LARP4
LMNB2
LMO3
LNX1
LONRF1
MAGEA12
MAPK9
MEIS2
MIEN1
MLLT10
MORF4L2
MSRB3
MSX2
MYL7
MYO15B
NEUROG3
NFYC
NKX3-2
NME7
NUP62CL
OAZ3
OIP5
OPLAH
OPTN
PADI4
PARVG
PDE6H
PIBF1
PKN1
PM20D2
POLR3C
POU2F1
PPIL1
PPIP5K2
PROP1
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
QRICH1
RAD23B
RBM39
RBPMS
RELA
SIX1
SMAD5
SMYD1
SORL1
SOX10
SSUH2
STAC
STRA8
TBX6
TCEA2
TENT5B
THADA
THAP1
TLX2
TLX3
TNPO2
TNXB
TP53BP1
TRIM73
TRIML2
TSC1
TSEN15
TTC19
TTC23
UBAC1
UFSP1
VAX2
VENTX
VEZF1
VPS9D1
XPOT
ZBTB24
ZBTB4
ZFHX2
ZFHX3
ZFP1
ZFP91
ZIM2
ZMYND12
ZNF148
ZNF319
ZNF34
ZNF384
ZNF410
ZNF574
Entrez ID
5626
11281
HPRD ID
03325
10162
Ensembl ID
ENSG00000175325
ENSG00000106536
Uniprot IDs
A0A0G2JQ02
O75360
P78424
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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