PROP1 and C6orf15

Data Source:
BioGRID (two hybrid)

		PROP1	C6orf15
Description		PROP paired-like homeobox 1	chromosome 6 open reading frame 15
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex	Cellular_component Extracellular Matrix
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding	Molecular_function Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Pituitary Gland Development	Biological_process Extracellular Matrix Organization
Pathways
Drugs
Diseases		Pituitary Dwarfism (PD); Isolated growth hormone deficiency (IGHD); Short Stature and Pituitary Defects (SSPD); Insulin-like growth factor 1 deficiency (IGFD)
GWAS			Apolipoprotein B levels ( 32203549) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 29875488 28240269) Epstein-Barr virus immune response (EBNA-1) ( 23326239) Follicular lymphoma ( 20639881) Graves' disease ( 21841780) Hematology traits ( 23263863) Hypothyroidism ( 22493691) Inflammatory bowel disease ( 28067908) Leprosy ( 32421744) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Malaria ( 31844061) Nickel levels ( 26025379) Response to hepatitis B vaccine ( 29534301) Rosacea symptom severity ( 29771307) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848) Small cell lung carcinoma ( 28604730) Thyrotoxic hypokalemic periodic paralysis and Graves disease ( 31050781) Ulcerative colitis ( 28067908) White blood cell count ( 21738480)
Interacting Genes		54 interacting genes: ABHD11 ARSA BATF2 C11orf1 C19orf54 C1orf94 C6orf15 C9orf24 COX6B2 CRYBA1 CYSRT1 DAZAP2 EFEMP2 FAM166A FAM168A HDHD3 HESX1 HNRNPF HOXA1 INTS11 KHDC1 KRTAP13-1 KRTAP19-1 KRTAP19-6 KRTAP19-7 KRTAP6-3 KRTAP8-1 MAGED1 METTL15 METTL27 NR1D2 OLIG3 OXER1 P4HA3 PITX2 PLEKHB2 POU6F2 PSMB11 PSMB4 RNF144B RNF4 SMUG1 SUMO1 TBX22 TEKT4 TEKT5 TENT5B TINAGL1 TLE5 TMEM42 TRIM42 UBE2I UFSP1 ZNF503	5 interacting genes: KRTAP6-2 PROP1 UBQLN2 VENTX YTHDF1
Entrez ID		5626	29113
HPRD ID		03325	12856
Ensembl ID		ENSG00000175325	ENSG00000204542
Uniprot IDs		A0A0G2JQ02 O75360	M1T2K5 Q6UXA7
PDB IDs
Enriched GO Terms of Interacting Partners?
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