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PROP1 and METTL27
Data Source:
BioGRID
(two hybrid)
PROP1
METTL27
Description
PROP paired-like homeobox 1
methyltransferase like 27
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Transcription Regulator Complex
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Protein Binding
Sequence-specific Double-stranded DNA Binding
Protein Binding
Methyltransferase Activity
Biological Process
Regulation Of Transcription By RNA Polymerase II
Central Nervous System Development
Pituitary Gland Development
Pathways
Drugs
Diseases
Pituitary Dwarfism (PD); Isolated growth hormone deficiency (IGHD); Short Stature and Pituitary Defects (SSPD); Insulin-like growth factor 1 deficiency (IGFD)
GWAS
Interacting Genes
54 interacting genes:
ABHD11
ARSA
BATF2
C11orf1
C19orf54
C1orf94
C6orf15
C9orf24
COX6B2
CRYBA1
CYSRT1
DAZAP2
EFEMP2
FAM166A
FAM168A
HDHD3
HESX1
HNRNPF
HOXA1
INTS11
KHDC1
KRTAP13-1
KRTAP19-1
KRTAP19-6
KRTAP19-7
KRTAP6-3
KRTAP8-1
MAGED1
METTL15
METTL27
NR1D2
OLIG3
OXER1
P4HA3
PITX2
PLEKHB2
POU6F2
PSMB11
PSMB4
RNF144B
RNF4
SMUG1
SUMO1
TBX22
TEKT4
TEKT5
TENT5B
TINAGL1
TLE5
TMEM42
TRIM42
UBE2I
UFSP1
ZNF503
29 interacting genes:
A1CF
ATXN1
ATXN1L
CCDC120
CSTF2
DOK6
EFHC1
ENKD1
FOXC2
GLYCTK
GPANK1
GRB2
HGS
KDM1A
LMO4
NOXA1
PITX1
PPP1R32
PRKAB2
PRMT6
PROP1
SNRPC
TBX6
TEKT3
TFG
TLX3
VPS37C
ZIC1
ZNF77
Entrez ID
5626
155368
HPRD ID
03325
15661
Ensembl ID
ENSG00000175325
ENSG00000165171
Uniprot IDs
A0A0G2JQ02
O75360
Q8N6F8
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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