AP1AR and KLC1

Data Source:
BioGRID (two hybrid)

		AP1AR	KLC1
Description		adaptor related protein complex 1 associated regulatory protein	kinesin light chain 1
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Early Endosome Late Endosome Golgi Apparatus Cytosol Transport Vesicle	Cytosol Kinesin Complex Microtubule Membrane Growth Cone Cytoplasmic Vesicle
	Molecular Function	Kinesin Binding AP-1 Adaptor Complex Binding	Motor Activity Protein Binding
	Biological Process	Negative Regulation Of Receptor Recycling Protein Transport Regulation Of Arp2/3 Complex-mediated Actin Nucleation Cellular Protein Localization Vesicle Targeting, Trans-Golgi To Endosome Negative Regulation Of Substrate Adhesion-dependent Cell Spreading Negative Regulation Of Cell Motility	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Movement Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Stress Granule Disassembly
Pathways			MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS		Body mass index ( 26426971)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Body mass index ( 28892062 25673413) Brain morphology (MOSTest) ( 32665545) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Schizophrenia ( 25056061) Smoking behaviour (cigarette pack-years) ( 30679032) Urate levels ( 31578528)
Interacting Genes		3 interacting genes: AP1G1 GGA1 KLC1	28 interacting genes: ADRB2 AP1AR APP ATCAY BNIP2 CLSTN1 ERBB2 F2RL1 HSPB1 KIF2A KIF5C KLC2 KRT31 LRSAM1 MAPK6 MAPK8IP1 MAPK8IP2 MAPK8IP3 NIN ODAD1 ODF1 PCM1 PLEKHM2 PTGER4 SNCA SPAG9 TACC3 YWHAB
Entrez ID		55435	3831
HPRD ID		12824	02489
Ensembl ID		ENSG00000138660	ENSG00000126214
Uniprot IDs		A0A024RDI1 Q63HQ0	Q07866 Q7RTQ2
PDB IDs			3NF1 5OJ8
Enriched GO Terms of Interacting Partners?
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