TMA16 and KLHL2

		TMA16	KLHL2
Description		translation machinery associated 16 homolog	kelch like family member 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus	Ruffle Cytoplasm Cytosol Actin Cytoskeleton Lamellipodium Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding	Actin Binding Protein Binding Identical Protein Binding
	Biological Process		Protein Ubiquitination Post-translational Protein Modification
Pathways			Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Small cell lung carcinoma ( 28604730)	Cognitive function ( 24684796) General cognitive ability ( 29844566) Neuroticism ( 27067015)
Interacting Genes		8 interacting genes: AP2M1 APP CASTOR1 IKBKG KLHL2 KRTAP10-7 NEDD4L TSPYL2	31 interacting genes: ACTC1 BCAM BYSL C20orf85 CCDC43 CDC37 CLK2 CUL3 CWC22 ELOA KEAP1 KLHL12 KLHL3 MFAP1 NAP1L2 NTAQ1 PADI6 PIBF1 POLR3C SDCBP TMA16 TNPO2 TRIM50 TXNDC12 UBE2C UBE2D1 UBE2I UCK1 WNK1 WNK4 ZNF114
Entrez ID		55319	11275
HPRD ID		07739	09311
Ensembl ID		ENSG00000198498	ENSG00000109466
Uniprot IDs		Q96EY4	B4DFZ5 E9PEX9 O95198
PDB IDs		6LSS 6LU8	2XN4 4CHB
Enriched GO Terms of Interacting Partners?
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