KLHL2 and PADI6

		KLHL2	PADI6
Description		kelch like family member 2	peptidyl arginine deiminase 6
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GO Annotations	Cellular Component	Ruffle Cytoplasm Cytosol Actin Cytoskeleton Lamellipodium Cul3-RING Ubiquitin Ligase Complex	Nucleus Cytoplasm Intermediate Filament Cytoskeleton
	Molecular Function	Actin Binding Protein Binding Identical Protein Binding	Protein-arginine Deiminase Activity Calcium Ion Binding Protein Binding
	Biological Process	Protein Ubiquitination Post-translational Protein Modification	Cytoskeleton Organization Cytoplasm Organization Histone Citrullination Regulation Of Translation By Machinery Localization
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Chromatin modifying enzymes
Drugs			Citrulline
Diseases
GWAS		Cognitive function ( 24684796) General cognitive ability ( 29844566) Neuroticism ( 27067015)	Basal cell carcinoma ( 24403052 25855136 18849993) Mean platelet volume ( 27863252)
Interacting Genes		31 interacting genes: ACTC1 BCAM BYSL C20orf85 CCDC43 CDC37 CLK2 CUL3 CWC22 ELOA KEAP1 KLHL12 KLHL3 MFAP1 NAP1L2 NTAQ1 PADI6 PIBF1 POLR3C SDCBP TMA16 TNPO2 TRIM50 TXNDC12 UBE2C UBE2D1 UBE2I UCK1 WNK1 WNK4 ZNF114	3 interacting genes: KLHL2 SUV39H1 ZNF526
Entrez ID		11275	353238
HPRD ID		09311	15095
Ensembl ID		ENSG00000109466	ENSG00000276747
Uniprot IDs		B4DFZ5 E9PEX9 O95198	Q6TGC4
PDB IDs		2XN4 4CHB	4DAT 4DAU
Enriched GO Terms of Interacting Partners?
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