KLHL2 and C20orf85

		KLHL2	C20orf85
Description		kelch like family member 2	chromosome 20 open reading frame 85
Image			No pdb structure
GO Annotations	Cellular Component	Ruffle Cytoplasm Cytosol Actin Cytoskeleton Lamellipodium Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Actin Binding Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Protein Ubiquitination Post-translational Protein Modification
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Cognitive function ( 24684796) General cognitive ability ( 29844566) Neuroticism ( 27067015)	Advanced age-related macular degeneration ( 26691988) Obesity-related traits ( 23251661)
Interacting Genes		31 interacting genes: ACTC1 BCAM BYSL C20orf85 CCDC43 CDC37 CLK2 CUL3 CWC22 ELOA KEAP1 KLHL12 KLHL3 MFAP1 NAP1L2 NTAQ1 PADI6 PIBF1 POLR3C SDCBP TMA16 TNPO2 TRIM50 TXNDC12 UBE2C UBE2D1 UBE2I UCK1 WNK1 WNK4 ZNF114	22 interacting genes: ACTN3 ALKBH7 ASPG CABP2 CACNB3 CASK CNOT2 DTX2 EFHC1 FHL2 KLHL2 KLHL20 KRTAP19-6 KRTAP3-1 KRTAP6-2 KRTAP8-1 LCN2 MAD2L2 OIP5 PFDN5 RBPMS TTC19
Entrez ID		11275	128602
HPRD ID		09311	12787
Ensembl ID		ENSG00000109466	ENSG00000124237
Uniprot IDs		B4DFZ5 E9PEX9 O95198	Q9H1P6
PDB IDs		2XN4 4CHB
Enriched GO Terms of Interacting Partners?
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