KLHL2 and ZNF114

Data Source:
BioGRID (two hybrid, two hybrid)

		KLHL2	ZNF114
Description		kelch like family member 2	zinc finger protein 114
Image			No pdb structure
GO Annotations	Cellular Component	Ruffle Cytoplasm Cytosol Actin Cytoskeleton Lamellipodium Cul3-RING Ubiquitin Ligase Complex	Nucleus Extracellular Exosome
	Molecular Function	Actin Binding Protein Binding Identical Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Molecular_function Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Protein Ubiquitination Post-translational Protein Modification	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Biological_process
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Generic Transcription Pathway
Drugs
Diseases
GWAS		Cognitive function ( 24684796) General cognitive ability ( 29844566) Neuroticism ( 27067015)
Interacting Genes		31 interacting genes: ACTC1 BCAM BYSL C20orf85 CCDC43 CDC37 CLK2 CUL3 CWC22 ELOA KEAP1 KLHL12 KLHL3 MFAP1 NAP1L2 NTAQ1 PADI6 PIBF1 POLR3C SDCBP TMA16 TNPO2 TRIM50 TXNDC12 UBE2C UBE2D1 UBE2I UCK1 WNK1 WNK4 ZNF114	10 interacting genes: CENATAC CLIP4 KIAA0753 KLHL2 KRTAP10-6 MAP7 MYO15B SUFU TPPP ZNF8
Entrez ID		11275	163071
HPRD ID		09311	14463
Ensembl ID		ENSG00000109466	ENSG00000178150
Uniprot IDs		B4DFZ5 E9PEX9 O95198	Q8NC26
PDB IDs		2XN4 4CHB
Enriched GO Terms of Interacting Partners?
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