GIPC2 and CTRC

Data Source:
BioGRID (two hybrid)

		GIPC2	CTRC
Description		GIPC PDZ domain containing family member 2	chymotrypsin C
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GO Annotations	Cellular Component	Cytoplasm Extracellular Exosome	Extracellular Region
	Molecular Function	Molecular_function Protein Binding Identical Protein Binding	Serine-type Endopeptidase Activity Protein Binding Peptidase Activity
	Biological Process	Biological_process	Proteolysis Cellular Calcium Ion Homeostasis Cobalamin Metabolic Process
Pathways			Cobalamin (Cbl, vitamin B12) transport and metabolism
Drugs
Diseases			Tropical calcific pancreatitis Hereditary pancreatitis; Hereditary chronic pancreatitis
GWAS		Body mass index ( 29273807) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) End-stage kidney disease ( 31178898) Hand grip strength ( 29691431) Height ( 20881960 25282103) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference ( 25673412) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Mean corpuscular hemoglobin concentration ( 32888494) Platelet distribution width ( 32888494) Post bronchodilator FEV1 ( 26634245) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Severe influenza A (H1N1) infection ( 26379185)	Alcoholic chronic pancreatitis ( 28754779)
Interacting Genes		14 interacting genes: CTRC FZD3 IGSF21 IRF4 LZTS2 PATJ PLEKHA2 PTN SETDB1 SP100 UBE2I UNC119 ZBTB26 ZCCHC7	20 interacting genes: CYSRT1 GIPC2 KRT34 KRTAP1-1 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP3-1 KRTAP6-2 KRTAP9-2 MDFI NEDD8 NFKBID PHKG1 SERPINA3 SPINK1 ST13 TEX37 UBC VGLL3
Entrez ID		54810	11330
HPRD ID		17040	03242
Ensembl ID		ENSG00000137960	ENSG00000162438
Uniprot IDs		A0A384P5H2 Q8TF65	Q99895
PDB IDs		3GGE	4H4F
Enriched GO Terms of Interacting Partners?
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