CTRC and ST13

Data Source:
BioGRID (enzymatic study)

		CTRC	ST13
Description		chymotrypsin C	ST13 Hsp70 interacting protein
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GO Annotations	Cellular Component	Extracellular Region	Cytoplasm Cytosol Protein-containing Complex Extracellular Exosome
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding Peptidase Activity	Protein Binding Protein Domain Specific Binding Hsp70 Protein Binding Protein-macromolecule Adaptor Activity Heat Shock Protein Binding DATP Binding Identical Protein Binding Protein-containing Complex Binding Protein Dimerization Activity Unfolded Protein Binding Chaperone Binding
	Biological Process	Proteolysis Cellular Calcium Ion Homeostasis Cobalamin Metabolic Process	Protein Folding Response To Bacterium Chaperone Cofactor-dependent Protein Refolding Negative Regulation Of Protein Refolding Protein-containing Complex Assembly
Pathways		Cobalamin (Cbl, vitamin B12) transport and metabolism	Regulation of HSF1-mediated heat shock response
Drugs
Diseases		Tropical calcific pancreatitis Hereditary pancreatitis; Hereditary chronic pancreatitis
GWAS		Alcoholic chronic pancreatitis ( 28754779)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Feeling nervous ( 29500382) Refractive error ( 32231278)
Interacting Genes		20 interacting genes: CYSRT1 GIPC2 KRT34 KRTAP1-1 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP3-1 KRTAP6-2 KRTAP9-2 MDFI NEDD8 NFKBID PHKG1 SERPINA3 SPINK1 ST13 TEX37 UBC VGLL3	20 interacting genes: ALB APOE ASF1A CD101 CDC42 CTRC CXCR2 F2 HSP90AA1 HSPA1A HSPA1B HSPA4 HSPA8 NOS3 OLFM2 PSEN1 PTGER4 SMAD2 TTR VAV2
Entrez ID		11330	6767
HPRD ID		03242	08426
Ensembl ID		ENSG00000162438	ENSG00000100380
Uniprot IDs		Q99895	A0A140VKA6 B4E0U6 P50502 Q0IJ56
PDB IDs		4H4F	1UZS
Enriched GO Terms of Interacting Partners?
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