CTRC and VGLL3

Data Source:
BioGRID (two hybrid)

		CTRC	VGLL3
Description		chymotrypsin C	vestigial like family member 3
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region	Nucleus
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding Peptidase Activity
	Biological Process	Proteolysis Cellular Calcium Ion Homeostasis Cobalamin Metabolic Process	Regulation Of Transcription By RNA Polymerase II
Pathways		Cobalamin (Cbl, vitamin B12) transport and metabolism
Drugs
Diseases		Tropical calcific pancreatitis Hereditary pancreatitis; Hereditary chronic pancreatitis
GWAS		Alcoholic chronic pancreatitis ( 28754779)	Adventurousness ( 30643258) Breast cancer ( 29059683) General risk tolerance (MTAG) ( 30643258) HDL cholesterol levels ( 32203549) Menarche (age at onset) ( 27182965 21102462) Metabolite levels ( 23823483) Molybdenum levels ( 26025379) Number of sexual partners ( 30643258) Obesity-related traits ( 23251661) Prostate cancer ( 31562322 26443449) Pubertal anthropometrics ( 23449627) Response to TNF inhibitor in rheumatoid arthritis (change in swollen 28-joint count) ( 30166627) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking status (ever vs never smokers) ( 30643258) Triglyceride levels ( 32203549)
Interacting Genes		20 interacting genes: CYSRT1 GIPC2 KRT34 KRTAP1-1 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP3-1 KRTAP6-2 KRTAP9-2 MDFI NEDD8 NFKBID PHKG1 SERPINA3 SPINK1 ST13 TEX37 UBC VGLL3	65 interacting genes: CDPF1 CERCAM CNFN CTRC CYSRT1 DTX2 ESM1 FAM168B FRS3 HGS INCA1 KPRP KRTAP1-1 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP13-2 KRTAP15-1 KRTAP19-1 KRTAP19-2 KRTAP19-6 KRTAP19-7 KRTAP3-1 KRTAP3-3 KRTAP4-11 KRTAP4-2 KRTAP5-11 KRTAP5-6 KRTAP6-1 KRTAP6-2 KRTAP9-2 KRTAP9-3 KRTAP9-8 LASP1 LENG8 MDFI MYO15B OXER1 PCSK5 PITX1 PITX2 PLA2G10 POGZ POU2AF1 PRR22 RBPMS RUSC1 SMARCC1 SMOC1 TBX15 TEAD1 TEAD2 TEAD3 TEAD4 TEX37 TRIM42 TSC1 TSPAN4 UFSP1 YPEL3 ZNF34
Entrez ID		11330	389136
HPRD ID		03242	13431
Ensembl ID		ENSG00000162438	ENSG00000206538
Uniprot IDs		Q99895	A8MV65
PDB IDs		4H4F
Enriched GO Terms of Interacting Partners?
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