GIPC2 and FZD3

Data Source:
HPRD (in vivo)

		GIPC2	FZD3
Description		GIPC PDZ domain containing family member 2	frizzled class receptor 3
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Extracellular Exosome	Cytoplasm Plasma Membrane Cell Surface Integral Component Of Membrane Apical Plasma Membrane Lateral Plasma Membrane Axon Dendrite Filopodium Tip Neuronal Cell Body Presynaptic Active Zone
	Molecular Function	Molecular_function Protein Binding Identical Protein Binding	G Protein-coupled Receptor Activity Protein Binding Wnt-protein Binding PDZ Domain Binding Wnt-activated Receptor Activity
	Biological Process	Biological_process	Establishment Of Planar Polarity Neuron Migration Neural Tube Closure Hair Follicle Development Positive Regulation Of Neuroblast Proliferation G Protein-coupled Receptor Signaling Pathway Wnt Signaling Pathway, Calcium Modulating Pathway Neuron Differentiation Cell Proliferation In Midbrain Non-canonical Wnt Signaling Pathway Post-anal Tail Morphogenesis Dopaminergic Neuron Axon Guidance Serotonergic Neuron Axon Guidance Inner Ear Morphogenesis Response To Drug Negative Regulation Of Mitotic Cell Cycle, Embryonic Response To Electrical Stimulus Canonical Wnt Signaling Pathway Wnt Signaling Pathway, Planar Cell Polarity Pathway Sympathetic Ganglion Development Commissural Neuron Axon Guidance Negative Regulation Of Execution Phase Of Apoptosis Midbrain Morphogenesis Planar Cell Polarity Pathway Involved In Axon Guidance
Pathways			Class B/2 (Secretin family receptors) Ca2+ pathway Ca2+ pathway PCP/CE pathway PCP/CE pathway Asymmetric localization of PCP proteins Asymmetric localization of PCP proteins
Drugs
Diseases
GWAS		Body mass index ( 29273807) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) End-stage kidney disease ( 31178898) Hand grip strength ( 29691431) Height ( 20881960 25282103) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference ( 25673412) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Mean corpuscular hemoglobin concentration ( 32888494) Platelet distribution width ( 32888494) Post bronchodilator FEV1 ( 26634245) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Severe influenza A (H1N1) infection ( 26379185)
Interacting Genes		14 interacting genes: CTRC FZD3 IGSF21 IRF4 LZTS2 PATJ PLEKHA2 PTN SETDB1 SP100 UBE2I UNC119 ZBTB26 ZCCHC7	3 interacting genes: GIPC1 GIPC2 GIPC3
Entrez ID		54810	7976
HPRD ID		17040	05849
Ensembl ID		ENSG00000137960	ENSG00000104290
Uniprot IDs		A0A384P5H2 Q8TF65	Q9NPG1
PDB IDs		3GGE
Enriched GO Terms of Interacting Partners?
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