Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
CTBP1 and FANCC
Data Source:
BioGRID
(two hybrid)
CTBP1
FANCC
Description
C-terminal binding protein 1
FA complementation group C
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Transcription Repressor Complex
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Fanconi Anaemia Nuclear Complex
Molecular Function
RNA Polymerase II Transcription Corepressor Binding
Transcription Corepressor Activity
Protein Binding
Protein C-terminus Binding
Transcription Factor Binding
Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor
Protein Domain Specific Binding
Identical Protein Binding
NAD Binding
Repressing Transcription Factor Binding
Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Chromatin Silencing
Protein Phosphorylation
Negative Regulation Of Cell Population Proliferation
Viral Genome Replication
Positive Regulation Of Histone Deacetylation
Negative Regulation Of Histone Acetylation
Negative Regulation Of Transcription, DNA-templated
White Fat Cell Differentiation
Regulation Of Cell Cycle
Negative Regulation Of Histone H4 Acetylation
Myeloid Cell Homeostasis
DNA Repair
Nucleotide-excision Repair
Germ Cell Development
Removal Of Superoxide Radicals
Cellular Response To Oxidative Stress
Interstrand Cross-link Repair
Brain Morphogenesis
Protein-containing Complex Assembly
Neuronal Stem Cell Population Maintenance
Pathways
Deactivation of the beta-catenin transactivating complex
SUMOylation of transcription cofactors
Repression of WNT target genes
Signaling by TCF7L2 mutants
Fanconi Anemia Pathway
TP53 Regulates Transcription of DNA Repair Genes
Drugs
Formic acid
Diseases
Fanconi anemia
GWAS
Type 2 diabetes (
31118516
32499647
)
Birth weight (
31043758
)
Hematocrit (
32888494
)
Offspring birth weight (
31043758
)
Polycystic ovary syndrome (
26284813
)
Interacting Genes
92 interacting genes:
ACTL6B
AKAP9
APC
ARNT2
ATXN1L
BCAS3
BCL3
BMPR2
BRCA1
CBX4
CDC23
CDKN2D
CEP68
CHD3
CREBBP
CRY2
CTBP2
CTNNA1
DGCR6
DMRTB1
EEF1D
ELAC2
ELK3
EP300
FANCC
FANCF
FANCG
FANCL
FOXP1
FOXP2
FUNDC1
GTF2B
H3-4
HDAC1
HDAC2
HDAC3
HDAC4
HDAC5
HDAC9
HEMGN
HIC1
HOXB5
HTT
IKZF1
IKZF2
KAT2B
KDM1A
KLF12
KLF3
LCORL
LNX1
MAML2
MAPK9
MARCHF10
MECOM
NME2
NOL4
NOL4L
NOS1
NRIP1
NTAQ1
ORC4
PIAS2
PLCB1
PNN
PRKAA1
PRKCI
RAI2
RB1
RBBP5
RBBP8
RBM14
RCOR1
RNF111
SIN3A
SNRPN
SOBP
SPEN
TBP
TCF4
TEAD4
TERF2
TERF2IP
TGIF1
THAP11
TSHZ3
ZBP1
ZBTB18
ZEB1
ZEB2
ZFPM2
ZNF219
54 interacting genes:
APC
AZIN1
BMPR1A
BUB1
CAPN10
CCNA2
CCND1
CDK1
CTBP1
DLC1
DNAJB1
EGFR
FANCA
FANCD2
FANCE
FANCF
FANCG
FBXW7
GSTP1
HSP90AA1
HSP90B1
HSPA1A
HSPA4
HSPA8
IK
KRAS
KRT1
MEOX2
MLH3
MT-ATP6
MUTYH
NRAS
PDGFRL
PIK3CA
PMS2
POR
PRDX3
PRPF31
PTPN12
PTPRJ
RB1
RPL18
RPS3A
SMAD4
SPTA1
SPTAN1
SRC
STAT1
STMN1
STMN2
TCERG1
TGFBR2
USP14
ZBTB32
Entrez ID
1487
2176
HPRD ID
04015
01967
Ensembl ID
ENSG00000159692
ENSG00000158169
Uniprot IDs
Q13363
X5D8Y5
A0A024R9N2
A0A087WW44
B4E3W2
Q00597
PDB IDs
1MX3
4LCE
4U6Q
4U6S
6CDF
6CDR
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?