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CTBP1 and RAI2
Data Source:
BioGRID
(two hybrid)
CTBP1
RAI2
Description
C-terminal binding protein 1
retinoic acid induced 2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Transcription Repressor Complex
Cellular_component
Molecular Function
RNA Polymerase II Transcription Corepressor Binding
Transcription Corepressor Activity
Protein Binding
Protein C-terminus Binding
Transcription Factor Binding
Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor
Protein Domain Specific Binding
Identical Protein Binding
NAD Binding
Repressing Transcription Factor Binding
Molecular_function
Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Chromatin Silencing
Protein Phosphorylation
Negative Regulation Of Cell Population Proliferation
Viral Genome Replication
Positive Regulation Of Histone Deacetylation
Negative Regulation Of Histone Acetylation
Negative Regulation Of Transcription, DNA-templated
White Fat Cell Differentiation
Regulation Of Cell Cycle
Negative Regulation Of Histone H4 Acetylation
Embryo Development Ending In Birth Or Egg Hatching
Pathways
Deactivation of the beta-catenin transactivating complex
SUMOylation of transcription cofactors
Repression of WNT target genes
Signaling by TCF7L2 mutants
Drugs
Formic acid
Diseases
GWAS
Type 2 diabetes (
31118516
32499647
)
Prostate-specific antigen levels (
28139693
)
Interacting Genes
92 interacting genes:
ACTL6B
AKAP9
APC
ARNT2
ATXN1L
BCAS3
BCL3
BMPR2
BRCA1
CBX4
CDC23
CDKN2D
CEP68
CHD3
CREBBP
CRY2
CTBP2
CTNNA1
DGCR6
DMRTB1
EEF1D
ELAC2
ELK3
EP300
FANCC
FANCF
FANCG
FANCL
FOXP1
FOXP2
FUNDC1
GTF2B
H3-4
HDAC1
HDAC2
HDAC3
HDAC4
HDAC5
HDAC9
HEMGN
HIC1
HOXB5
HTT
IKZF1
IKZF2
KAT2B
KDM1A
KLF12
KLF3
LCORL
LNX1
MAML2
MAPK9
MARCHF10
MECOM
NME2
NOL4
NOL4L
NOS1
NRIP1
NTAQ1
ORC4
PIAS2
PLCB1
PNN
PRKAA1
PRKCI
RAI2
RB1
RBBP5
RBBP8
RBM14
RCOR1
RNF111
SIN3A
SNRPN
SOBP
SPEN
TBP
TCF4
TEAD4
TERF2
TERF2IP
TGIF1
THAP11
TSHZ3
ZBP1
ZBTB18
ZEB1
ZEB2
ZFPM2
ZNF219
12 interacting genes:
APP
APPL2
ATXN1
CTBP1
CTBP2
DOK5
FHL2
SGTB
TRIM55
TRIM63
UBQLN1
UBQLN4
Entrez ID
1487
10742
HPRD ID
04015
02199
Ensembl ID
ENSG00000159692
ENSG00000131831
Uniprot IDs
Q13363
X5D8Y5
A0A024RBZ8
B2RBE9
B3KPD7
Q9Y5P3
PDB IDs
1MX3
4LCE
4U6Q
4U6S
6CDF
6CDR
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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