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EXOSC10 and PTGES2
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
EXOSC10
PTGES2
Description
exosome component 10
prostaglandin E synthase 2
Image
No pdb structure
GO Annotations
Cellular Component
Nuclear Exosome (RNase Complex)
Exosome (RNase Complex)
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Cytosol
Membrane
Transcriptionally Active Chromatin
Golgi Membrane
Extracellular Region
Nucleus
Mitochondrion
Cytosol
Integral Component Of Membrane
Azurophil Granule Lumen
Perinuclear Region Of Cytoplasm
Molecular Function
Nucleotide Binding
3'-5'-exoribonuclease Activity
RNA Binding
Single-stranded RNA Binding
Exoribonuclease Activity
Protein Binding
Telomerase RNA Binding
DNA Binding
Protein Binding
Protein Disulfide Oxidoreductase Activity
Lyase Activity
Heme Binding
Glutathione Binding
Prostaglandin-E Synthase Activity
Biological Process
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Maturation Of 5.8S RRNA
Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA)
Nuclear-transcribed MRNA Catabolic Process
RRNA Processing
Dosage Compensation By Inactivation Of X Chromosome
Negative Regulation Of Telomere Maintenance Via Telomerase
Nuclear MRNA Surveillance
CUT Catabolic Process
Nuclear Polyadenylation-dependent RRNA Catabolic Process
Nuclear Polyadenylation-dependent SnoRNA Catabolic Process
Nuclear Polyadenylation-dependent SnRNA Catabolic Process
Nuclear Polyadenylation-dependent TRNA Catabolic Process
Nuclear Polyadenylation-dependent CUT Catabolic Process
Nuclear Polyadenylation-dependent Antisense Transcript Catabolic Process
Histone MRNA Catabolic Process
Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription
Polyadenylation-dependent SnoRNA 3'-end Processing
Regulation Of Telomerase RNA Localization To Cajal Body
Lipid Metabolic Process
Glutathione Metabolic Process
Cyclooxygenase Pathway
Neutrophil Degranulation
Positive Regulation Of Transcription, DNA-templated
Pathways
Major pathway of rRNA processing in the nucleolus and cytosol
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
Neutrophil degranulation
Drugs
Diseases
Penile cancer
GWAS
Beard thickness (
26926045
)
Heel bone mineral density (
30598549
)
Intraocular pressure (
29617998
)
Body mass index (
26426971
)
Interacting Genes
37 interacting genes:
ALDH1B1
B9D1
CHPF
CIB1
DIS3
DXO
EIF3M
EXOSC4
EXOSC5
EXOSC6
EXOSC7
EXOSC8
FERMT3
FOXRED1
IMMT
LCAT
LSM2
LSM8
MPHOSPH6
NOMO1
NOMO2
PALS2
PTGES2
RPE
RUVBL2
SCRIB
SKIV2L
SSRP1
SUMO2
TARDBP
TOX4
TTN
UPF2
USP16
USP21
XRN1
XRN2
5 interacting genes:
ADRB2
C1orf189
CEBPB
EXOSC10
PTGFR
Entrez ID
5394
80142
HPRD ID
16180
07458
Ensembl ID
ENSG00000171824
ENSG00000148334
Uniprot IDs
Q01780
A6NHH0
B3KPZ2
B4DWP1
Q9H7Z7
PDB IDs
2CPR
3SAF
3SAG
3SAH
6D6Q
6D6R
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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