PTGES2 and C1orf189

Data Source:
BioGRID (two hybrid)

		PTGES2	C1orf189
Description		prostaglandin E synthase 2	chromosome 1 open reading frame 189
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extracellular Region Nucleus Mitochondrion Cytosol Integral Component Of Membrane Azurophil Granule Lumen Perinuclear Region Of Cytoplasm
	Molecular Function	DNA Binding Protein Binding Protein Disulfide Oxidoreductase Activity Lyase Activity Heme Binding Glutathione Binding Prostaglandin-E Synthase Activity	Protein Binding
	Biological Process	Lipid Metabolic Process Glutathione Metabolic Process Cyclooxygenase Pathway Neutrophil Degranulation Positive Regulation Of Transcription, DNA-templated
Pathways		Synthesis of Prostaglandins (PG) and Thromboxanes (TX) Neutrophil degranulation
Drugs
Diseases		Penile cancer
GWAS		Body mass index ( 26426971)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cooked vegetable consumption ( 32066663) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) Smoking status (ever vs never smokers) ( 30643258) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		5 interacting genes: ADRB2 C1orf189 CEBPB EXOSC10 PTGFR	2 interacting genes: NME7 PTGES2
Entrez ID		80142	388701
HPRD ID		07458	17373
Ensembl ID		ENSG00000148334	ENSG00000163263
Uniprot IDs		A6NHH0 B3KPZ2 B4DWP1 Q9H7Z7	Q5VU69
PDB IDs
Enriched GO Terms of Interacting Partners?
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