Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
EXOSC10 and EIF3M
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
EXOSC10
EIF3M
Description
exosome component 10
eukaryotic translation initiation factor 3 subunit M
Image
GO Annotations
Cellular Component
Nuclear Exosome (RNase Complex)
Exosome (RNase Complex)
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Cytosol
Membrane
Transcriptionally Active Chromatin
Cytosol
Eukaryotic Translation Initiation Factor 3 Complex
Eukaryotic 43S Preinitiation Complex
Eukaryotic 48S Preinitiation Complex
Eukaryotic Translation Initiation Factor 3 Complex, EIF3m
Molecular Function
Nucleotide Binding
3'-5'-exoribonuclease Activity
RNA Binding
Single-stranded RNA Binding
Exoribonuclease Activity
Protein Binding
Telomerase RNA Binding
Translation Initiation Factor Activity
Protein Binding
Translation Initiation Factor Binding
Biological Process
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Maturation Of 5.8S RRNA
Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA)
Nuclear-transcribed MRNA Catabolic Process
RRNA Processing
Dosage Compensation By Inactivation Of X Chromosome
Negative Regulation Of Telomere Maintenance Via Telomerase
Nuclear MRNA Surveillance
CUT Catabolic Process
Nuclear Polyadenylation-dependent RRNA Catabolic Process
Nuclear Polyadenylation-dependent SnoRNA Catabolic Process
Nuclear Polyadenylation-dependent SnRNA Catabolic Process
Nuclear Polyadenylation-dependent TRNA Catabolic Process
Nuclear Polyadenylation-dependent CUT Catabolic Process
Nuclear Polyadenylation-dependent Antisense Transcript Catabolic Process
Histone MRNA Catabolic Process
Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription
Polyadenylation-dependent SnoRNA 3'-end Processing
Regulation Of Telomerase RNA Localization To Cajal Body
Formation Of Cytoplasmic Translation Initiation Complex
Cytoplasmic Translational Initiation
Translational Initiation
Viral Process
Pathways
Major pathway of rRNA processing in the nucleolus and cytosol
L13a-mediated translational silencing of Ceruloplasmin expression
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS
Beard thickness (
26926045
)
Heel bone mineral density (
30598549
)
Intraocular pressure (
29617998
)
Menopause (age at onset) (
26414677
)
Interacting Genes
37 interacting genes:
ALDH1B1
B9D1
CHPF
CIB1
DIS3
DXO
EIF3M
EXOSC4
EXOSC5
EXOSC6
EXOSC7
EXOSC8
FERMT3
FOXRED1
IMMT
LCAT
LSM2
LSM8
MPHOSPH6
NOMO1
NOMO2
PALS2
PTGES2
RPE
RUVBL2
SCRIB
SKIV2L
SSRP1
SUMO2
TARDBP
TOX4
TTN
UPF2
USP16
USP21
XRN1
XRN2
10 interacting genes:
ABI3
APP
EIF3F
EXOSC10
HSPB1
METTL3
SRPK1
TRIML2
ZMYND10
ZNF783
Entrez ID
5394
10480
HPRD ID
16180
09969
Ensembl ID
ENSG00000171824
ENSG00000149100
Uniprot IDs
Q01780
Q7L2H7
PDB IDs
2CPR
3SAF
3SAG
3SAH
6D6Q
6D6R
3J8B
3J8C
6FEC
6YBD
6ZMW
6ZON
6ZP4
6ZVJ
7A09
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?