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EXOSC10 and SSRP1
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
EXOSC10
SSRP1
Description
exosome component 10
structure specific recognition protein 1
Image
GO Annotations
Cellular Component
Nuclear Exosome (RNase Complex)
Exosome (RNase Complex)
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Cytosol
Membrane
Transcriptionally Active Chromatin
Nucleoplasm
Nucleolus
FACT Complex
Molecular Function
Nucleotide Binding
3'-5'-exoribonuclease Activity
RNA Binding
Single-stranded RNA Binding
Exoribonuclease Activity
Protein Binding
Telomerase RNA Binding
DNA Binding
RNA Binding
Protein Binding
Nucleosome Binding
Histone Binding
Biological Process
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Maturation Of 5.8S RRNA
Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA)
Nuclear-transcribed MRNA Catabolic Process
RRNA Processing
Dosage Compensation By Inactivation Of X Chromosome
Negative Regulation Of Telomere Maintenance Via Telomerase
Nuclear MRNA Surveillance
CUT Catabolic Process
Nuclear Polyadenylation-dependent RRNA Catabolic Process
Nuclear Polyadenylation-dependent SnoRNA Catabolic Process
Nuclear Polyadenylation-dependent SnRNA Catabolic Process
Nuclear Polyadenylation-dependent TRNA Catabolic Process
Nuclear Polyadenylation-dependent CUT Catabolic Process
Nuclear Polyadenylation-dependent Antisense Transcript Catabolic Process
Histone MRNA Catabolic Process
Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription
Polyadenylation-dependent SnoRNA 3'-end Processing
Regulation Of Telomerase RNA Localization To Cajal Body
DNA Replication
DNA Repair
Transcription By RNA Polymerase II
Transcription Elongation From RNA Polymerase II Promoter
Viral Process
Regulation Of Signal Transduction By P53 Class Mediator
Regulation Of Chromatin Organization
Pathways
Major pathway of rRNA processing in the nucleolus and cytosol
Formation of RNA Pol II elongation complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
Regulation of TP53 Activity through Phosphorylation
RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Beard thickness (
26926045
)
Heel bone mineral density (
30598549
)
Intraocular pressure (
29617998
)
Interacting Genes
37 interacting genes:
ALDH1B1
B9D1
CHPF
CIB1
DIS3
DXO
EIF3M
EXOSC4
EXOSC5
EXOSC6
EXOSC7
EXOSC8
FERMT3
FOXRED1
IMMT
LCAT
LSM2
LSM8
MPHOSPH6
NOMO1
NOMO2
PALS2
PTGES2
RPE
RUVBL2
SCRIB
SKIV2L
SSRP1
SUMO2
TARDBP
TOX4
TTN
UPF2
USP16
USP21
XRN1
XRN2
22 interacting genes:
AURKA
CHD1
CHMP1B
CSNK2A1
DHX9
EXOSC10
H2AC20
H2AX
H2BC21
H3-3A
MCM4
MYCBP
NEK9
PTEN
RAN
ROBO2
SPI1
SREK1
SRF
SUMO2
SUPT16H
UBE2I
Entrez ID
5394
6749
HPRD ID
16180
05061
Ensembl ID
ENSG00000171824
ENSG00000149136
Uniprot IDs
Q01780
A0A024R4Z6
Q08945
PDB IDs
2CPR
3SAF
3SAG
3SAH
6D6Q
6D6R
4IFS
5UMR
5UMS
5VWE
6L1E
6L1R
6L34
6UPK
6UPL
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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