PTGES2 and PTGFR

Data Source:
HPRD (in vivo)

		PTGES2	PTGFR
Description		prostaglandin E synthase 2	prostaglandin F receptor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extracellular Region Nucleus Mitochondrion Cytosol Integral Component Of Membrane Azurophil Granule Lumen Perinuclear Region Of Cytoplasm	Extracellular Region Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	DNA Binding Protein Binding Protein Disulfide Oxidoreductase Activity Lyase Activity Heme Binding Glutathione Binding Prostaglandin-E Synthase Activity	Prostaglandin F Receptor Activity
	Biological Process	Lipid Metabolic Process Glutathione Metabolic Process Cyclooxygenase Pathway Neutrophil Degranulation Positive Regulation Of Transcription, DNA-templated	Inflammatory Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Parturition Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Response To Estradiol Response To Lipopolysaccharide Calcium-mediated Signaling Using Intracellular Calcium Source Negative Regulation Of Apoptotic Process Cellular Response To Prostaglandin D Stimulus
Pathways		Synthesis of Prostaglandins (PG) and Thromboxanes (TX) Neutrophil degranulation	Prostanoid ligand receptors G alpha (q) signalling events
Drugs			Travoprost Latanoprost Bimatoprost Dinoprost tromethamine Tafluprost Latanoprostene bunod
Diseases		Penile cancer
GWAS		Body mass index ( 26426971)	Bipolar disorder ( 22182935) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Lung function in never smokers (high FEV1 vs average FEV1) ( 26423011) Skin fluorescence in type 1 diabetes ( 27207532) Systolic blood pressure (alcohol consumption interaction) ( 24376456)
Interacting Genes		5 interacting genes: ADRB2 C1orf189 CEBPB EXOSC10 PTGFR	5 interacting genes: AGTR1 PTGDS PTGER1 PTGER2 PTGES2
Entrez ID		80142	5737
HPRD ID		07458	08988
Ensembl ID		ENSG00000148334	ENSG00000122420
Uniprot IDs		A6NHH0 B3KPZ2 B4DWP1 Q9H7Z7	P43088
PDB IDs
Enriched GO Terms of Interacting Partners?
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