PEA15 and LUC7L2

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PEA15	LUC7L2
Description		proliferation and apoptosis adaptor protein 15	LUC7 like 2, pre-mRNA splicing factor
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Microtubule Associated Complex	U1 SnRNP Nuclear Speck U2-type Prespliceosome
	Molecular Function	Protein Binding	RNA Binding MRNA Binding Protein Binding Enzyme Binding
	Biological Process	MAPK Cascade Activation Of MAPK Activity Apoptotic Process Carbohydrate Transport Response To Morphine Negative Regulation Of Glucose Import Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors	MRNA Splice Site Selection
Pathways		RAF-independent MAPK1/3 activation RAF/MAP kinase cascade
Drugs
Diseases
GWAS			Diisocyanate-induced asthma ( 25918132)
Interacting Genes		40 interacting genes: ABCD4 AK9 AKT1 ATP1B3 CACYBP CAMK2G CASP8 CEP120 COPS5 DNAJB1 DYRK1A FADD HTRA2 KLHL12 L1CAM LUC7L2 MAPK1 MAPK3 MTIF3 OSBPL1A PANK4 PDE4DIP PDPK1 PGM1 PLD1 PLD2 PPP4R3A PRKCA PUS3 RAMAC RPS6KA3 RPSA RSL24D1 SNRPG SON TALDO1 TENT4B TERF2IP TJP1 TRAPPC13	55 interacting genes: AIMP2 ALB ANTKMT APP APPBP2 ATF7IP ATRX CADPS CDC37 CDK4 CDK5RAP2 CEP126 CHD3 DZIP1 EXOC1 FXR1 GADD45G GSK3B HAP1 HDHD2 IKBKG ITPRID2 KLHL20 LPL MAN2A2 MAP1LC3B MEOX2 NAP1L5 NASP NAT9 NDEL1 NDUFA4L2 NEDD4 NFYA NKAP NSF NUTF2 OFD1 PDPK1 PEA15 PIK3R3 PTCD3 PTN SAT1 SETDB1 SRRM4 SRSF6 SRSF7 SVIL ULK2 UNC119 WASHC3 YWHAG ZCCHC10 ZRSR2
Entrez ID		8682	51631
HPRD ID		04579	17456
Ensembl ID		ENSG00000162734	ENSG00000146963
Uniprot IDs		B1AKZ4 B1AKZ5 Q15121 Q96FS5	Q9Y383
PDB IDs		4IZ5 4IZA 6P6B 6P6C
Enriched GO Terms of Interacting Partners?
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