PEA15 and RAMAC

Data Source:
BioGRID (two hybrid)

		PEA15	RAMAC
Description		proliferation and apoptosis adaptor protein 15	RNA guanine-7 methyltransferase activating subunit
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GO Annotations	Cellular Component	Nucleoplasm Cytosol Microtubule Associated Complex	Nucleus Nucleoplasm MRNA Cap Binding Complex MRNA Cap Methyltransferase Complex
	Molecular Function	Protein Binding	RNA Binding Protein Binding Enzyme Activator Activity
	Biological Process	MAPK Cascade Activation Of MAPK Activity Apoptotic Process Carbohydrate Transport Response To Morphine Negative Regulation Of Glucose Import Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors	7-methylguanosine MRNA Capping Methylation Recruitment Of MRNA Capping Enzyme To RNA Polymerase II Holoenzyme Complex Regulation Of Catalytic Activity RNA 5'-cap (guanine-N7)-methylation
Pathways		RAF-independent MAPK1/3 activation RAF/MAP kinase cascade
Drugs
Diseases
GWAS
Interacting Genes		40 interacting genes: ABCD4 AK9 AKT1 ATP1B3 CACYBP CAMK2G CASP8 CEP120 COPS5 DNAJB1 DYRK1A FADD HTRA2 KLHL12 L1CAM LUC7L2 MAPK1 MAPK3 MTIF3 OSBPL1A PANK4 PDE4DIP PDPK1 PGM1 PLD1 PLD2 PPP4R3A PRKCA PUS3 RAMAC RPS6KA3 RPSA RSL24D1 SNRPG SON TALDO1 TENT4B TERF2IP TJP1 TRAPPC13	47 interacting genes: AKAP8L BAG4 BPIFA1 C10orf55 CYSRT1 DAB1 DAZAP2 DMRTB1 FAM168B FOXI1 GOLGA2 HNRNPH1 HNRNPK INCA1 KRT15 KRT31 KRT33B KRTAP1-3 KRTAP8-1 LZTS2 MAGED1 MAPK1IP1L NAF1 OXER1 PEA15 PLSCR1 PLSCR4 POU2AF1 PRR3 PSMA3 RBMX RBMY1F RBPMS RHOXF2 RINT1 RNMT SF3B4 SNRPC TEKT3 TEKT4 TNS2 TRIM23 TRIM27 TRIM42 USP54 VPS37C WWOX
Entrez ID		8682	83640
HPRD ID		04579	12845
Ensembl ID		ENSG00000162734	ENSG00000169612
Uniprot IDs		B1AKZ4 B1AKZ5 Q15121 Q96FS5	Q9BTL3
PDB IDs		4IZ5 4IZA 6P6B 6P6C	5E8J
Enriched GO Terms of Interacting Partners?
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