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NUP54 and TRIM54
Data Source:
BioGRID
(two hybrid)
NUP54
TRIM54
Description
nucleoporin 54
tripartite motif containing 54
Image
GO Annotations
Cellular Component
Nuclear Envelope
Nuclear Membrane
Host Cell
Nuclear Pore Central Transport Channel
Cytoplasm
Microtubule
Microtubule Associated Complex
Z Disc
Molecular Function
Protein Binding
Structural Constituent Of Nuclear Pore
Identical Protein Binding
Protein-containing Complex Binding
Protein Binding
Microtubule Binding
Zinc Ion Binding
Ubiquitin Protein Ligase Activity
Biological Process
Regulation Of Glycolytic Process
MRNA Export From Nucleus
TRNA Export From Nucleus
Protein Targeting
NLS-bearing Protein Import Into Nucleus
Nuclear Pore Organization
Viral Process
Protein Sumoylation
Viral Transcription
Protein Localization To Nuclear Inner Membrane
Regulation Of Protein Import Into Nucleus
Regulation Of Gene Silencing By MiRNA
Intracellular Transport Of Virus
Regulation Of Cellular Response To Heat
Microtubule-based Process
Negative Regulation Of Microtubule Depolymerization
Signal Transduction
Multicellular Organism Development
Protein Ubiquitination
Cell Differentiation
Pathways
ISG15 antiviral mechanism
Transport of the SLBP independent Mature mRNA
Transport of the SLBP Dependant Mature mRNA
Transport of Mature mRNA Derived from an Intronless Transcript
Transport of Mature mRNA derived from an Intron-Containing Transcript
Rev-mediated nuclear export of HIV RNA
Transport of Ribonucleoproteins into the Host Nucleus
NS1 Mediated Effects on Host Pathways
Viral Messenger RNA Synthesis
NEP/NS2 Interacts with the Cellular Export Machinery
Regulation of Glucokinase by Glucokinase Regulatory Protein
Nuclear import of Rev protein
Vpr-mediated nuclear import of PICs
snRNP Assembly
SUMOylation of DNA damage response and repair proteins
SUMOylation of ubiquitinylation proteins
Nuclear Pore Complex (NPC) Disassembly
Regulation of HSF1-mediated heat shock response
SUMOylation of SUMOylation proteins
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA replication proteins
SUMOylation of DNA replication proteins
Transcriptional regulation by small RNAs
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)
tRNA processing in the nucleus
HCMV Early Events
HCMV Late Events
Postmitotic nuclear pore complex (NPC) reformation
Drugs
Diseases
GWAS
Hippocampal volume (
29274321
)
Mean corpuscular hemoglobin (
32888494
)
Interacting Genes
46 interacting genes:
AGR2
AP1B1
AP2B1
APC
BPIFA1
C14orf119
C1orf109
C21orf91
CCDC85B
CCHCR1
CDC23
CENPH
DCTN3
DGCR6
EFHC1
EIF3F
EXOC1
EXOC8
HAUS1
HAUS8
HGS
HOMER1
IFT20
KPNA1
KPNB1
KRT15
KRT27
KRT33B
NFKBID
NR3C1
NUP62
NUTF2
OIP5
PKNOX2
SMYD3
SOHLH1
SPG21
SSR1
TACC3
TCHP
TEKT1
TEX12
TPM3
TRIM54
VPS37C
ZWINT
317 interacting genes:
AAMDC
ABHD17C
ADCY4
AGFG1
AIFM2
AK2
AK3
ANKRD11
ANKRD45
ARFIP2
ARHGAP29
ARHGEF5
ARHGEF6
ARMC7
ATXN3
ATXN3L
ATXN7
BBX
BMF
BSCL2
BYSL
C14orf39
C1orf109
C1orf216
C1orf35
C1QTNF2
C2CD6
C2orf49
C8orf74
CALM3
CARD9
CAVIN2
CBX8
CCDC102B
CCDC146
CCDC17
CCDC26
CCDC28A
CCDC87
CCHCR1
CCNC
CDC37
CDK18
CDKAL1
CDKN1A
CENPX
CEP57L1
CEP68
CFAP100
CFAP206
CFAP53
CHCHD2
CHD2
CHD3
CKM
CLPP
CMIP
CNGA3
CRADD
CSNK2B
CTNNA3
CWF19L2
CYTH4
DAXX
DCAF8
DCLRE1B
DCUN1D1
DDX6
DEUP1
DNAL4
DNASE1L1
DPYSL4
DRG2
DTNB
DTX2
DUSP16
DVL3
DYNC2I2
DYNLL1
EHHADH
EIF4E2
ELMO1
ELOA
ENKD1
EPHB2
EPM2AIP1
EXOC7
EXOC8
EXOSC5
EXTL2
FAM110A
FAM124A
FAM124B
FAM161A
FAM50B
FAM90A1
FAM9A
FARS2
FBF1
FBXO16
FBXW2
FLNC
FMNL1
G2E3
GAS8
GEM
GIMAP2
GLP2R
GMCL1
GNG13
GNL3L
GTF2I
GTF2IRD2
GTF2IRD2B
HAUS1
HBG1
HDAC10
HGS
HMMR
HOXB5
HSF2
HSPB1
HYAL2
IL18RAP
IL36A
IL4I1
ING3
INPP5J
IQUB
ITGAE
ITPKB
JOSD1
KANK2
KAT14
KDM1A
KIF9
KIFC3
KLHL38
KLHL42
KPNA2
KRT1
KRT3
KRT4
KRT6A
KRT6B
KRT6C
KRT75
KRT76
KRT78
KRT79
KRT8
KRTAP11-1
KRTAP9-2
LENG1
LIN37
LINC00887
LMO1
LMO2
LMO3
LMO4
LNX1
LSM2
MAD2L2
MAOB
MAPK3
MBD3
MCM7
MEAF6
MFAP1
MGARP
MICAL2
MID2
MNS1
MRTFA
MSH5
MYLK2
MYO15B
MYO5B
NEK6
NGLY1
NTAQ1
NUP54
NUP58
OFCC1
OSGIN1
OSTF1
OTUB1
OTUB2
PABPC3
PAIP2
PARVG
PCDHGB1
PCDHGC3
PCSK7
PDZK1IP1
PICK1
PIK3R3
PIWIL1
PLEKHM1
PLK4
PPIG
PPP1R18
PRF1
PRKAB2
PRKG1
PRMT5
PRPF18
PRR35
PSMA1
PYGM
RAB35
RABGEF1
RAD23A
RAPSN
RASSF10
RBM15B
RBM41
RCOR3
RELT
RIMS3
RNF4
RSRC2
RUNX1T1
SCNM1
SDCBP
SEC14L4
SELE
SEMA4C
SENP3
SH2D1B
SHC3
SLC13A2
SLITRK3
SMARCD1
SMARCE1
SNF8
SOX14
SPG21
SPRING1
SSX2IP
STAM
STRC
STXBP4
STYXL1
SYCE3
SYTL5
TBC1D22B
TCAF1
TCAP
TCEA2
TCEANC
TCHP
TEAD4
TEPSIN
THAP4
THOC1
TJAP1
TLE6
TLR10
TMEM30A
TNFAIP1
TNR
TRIM55
TRIM63
TRIM69
TRIML2
TSG101
TSHZ3
TSPEAR
TSSK3
TTC23
TTC9C
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E3
UBE2I
UBE2N
UBE2U
UBE2V2
UBL4A
UCHL1
UCHL3
UCHL5
USHBP1
USP15
USP18
USP2
USP21
USP33
USP35
USP4
USP5
USP7
USP8
UTP14C
VAMP4
VCAM1
VCP
VPS28
VPS9D1
XAF1
YEATS4
YOD1
ZBTB16
ZFHX3
ZGPAT
ZNF180
ZNF182
ZNF250
ZNF267
ZNF366
ZNF417
ZNF572
ZNF587
ZNF667-AS1
Entrez ID
53371
57159
HPRD ID
06352
05928
Ensembl ID
ENSG00000138750
ENSG00000138100
Uniprot IDs
Q7Z3B4
Q9BYV2
PDB IDs
4JNU
4JNV
4JO7
4JO9
5IJN
5IJO
3Q1D
Enriched GO Terms of Interacting Partners
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