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NUP54 and AP1B1
Data Source:
BioGRID
(two hybrid)
NUP54
AP1B1
Description
nucleoporin 54
adaptor related protein complex 1 subunit beta 1
Image
GO Annotations
Cellular Component
Nuclear Envelope
Nuclear Membrane
Host Cell
Nuclear Pore Central Transport Channel
Golgi Membrane
Lysosomal Membrane
Golgi Apparatus
Cytosol
Clathrin Adaptor Complex
Cytoplasmic Vesicle Membrane
Clathrin-coated Vesicle Membrane
Trans-Golgi Network Membrane
Intracellular Membrane-bounded Organelle
Molecular Function
Protein Binding
Structural Constituent Of Nuclear Pore
Identical Protein Binding
Protein-containing Complex Binding
Protein Binding
Protein Kinase Binding
Clathrin Binding
Biological Process
Regulation Of Glycolytic Process
MRNA Export From Nucleus
TRNA Export From Nucleus
Protein Targeting
NLS-bearing Protein Import Into Nucleus
Nuclear Pore Organization
Viral Process
Protein Sumoylation
Viral Transcription
Protein Localization To Nuclear Inner Membrane
Regulation Of Protein Import Into Nucleus
Regulation Of Gene Silencing By MiRNA
Intracellular Transport Of Virus
Regulation Of Cellular Response To Heat
Kidney Development
Intracellular Protein Transport
Determination Of Left/right Symmetry
Heart Development
Vesicle-mediated Transport
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Regulation Of Defense Response To Virus By Virus
Pathways
ISG15 antiviral mechanism
Transport of the SLBP independent Mature mRNA
Transport of the SLBP Dependant Mature mRNA
Transport of Mature mRNA Derived from an Intronless Transcript
Transport of Mature mRNA derived from an Intron-Containing Transcript
Rev-mediated nuclear export of HIV RNA
Transport of Ribonucleoproteins into the Host Nucleus
NS1 Mediated Effects on Host Pathways
Viral Messenger RNA Synthesis
NEP/NS2 Interacts with the Cellular Export Machinery
Regulation of Glucokinase by Glucokinase Regulatory Protein
Nuclear import of Rev protein
Vpr-mediated nuclear import of PICs
snRNP Assembly
SUMOylation of DNA damage response and repair proteins
SUMOylation of ubiquitinylation proteins
Nuclear Pore Complex (NPC) Disassembly
Regulation of HSF1-mediated heat shock response
SUMOylation of SUMOylation proteins
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA replication proteins
SUMOylation of DNA replication proteins
Transcriptional regulation by small RNAs
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)
tRNA processing in the nucleus
HCMV Early Events
HCMV Late Events
Postmitotic nuclear pore complex (NPC) reformation
Nef mediated downregulation of MHC class I complex cell surface expression
MHC class II antigen presentation
Lysosome Vesicle Biogenesis
Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS
Hippocampal volume (
29274321
)
Carotid atherosclerosis in HIV infection (
20009918
)
Heel bone mineral density (
30598549
28869591
)
High light scatter reticulocyte count (
32888494
27863252
)
High light scatter reticulocyte percentage of red cells (
32888494
27863252
)
Immature fraction of reticulocytes (
32888494
27863252
)
Pancreatic cancer (
25086665
)
Reticulocyte count (
32888494
)
Reticulocyte fraction of red cells (
32888494
)
Interacting Genes
46 interacting genes:
AGR2
AP1B1
AP2B1
APC
BPIFA1
C14orf119
C1orf109
C21orf91
CCDC85B
CCHCR1
CDC23
CENPH
DCTN3
DGCR6
EFHC1
EIF3F
EXOC1
EXOC8
HAUS1
HAUS8
HGS
HOMER1
IFT20
KPNA1
KPNB1
KRT15
KRT27
KRT33B
NFKBID
NR3C1
NUP62
NUTF2
OIP5
PKNOX2
SMYD3
SOHLH1
SPG21
SSR1
TACC3
TCHP
TEKT1
TEX12
TPM3
TRIM54
VPS37C
ZWINT
43 interacting genes:
AGR3
AP1G1
AP1G2
AP1M2
ARF1
ARF5
ARF6
ARRB2
ATF7IP
ATM
ATR
BARD1
BUB1
BUB1B
CLTC
CREBBP
CRYBB1
FARS2
FMNL2
FNDC11
GPANK1
GTF2I
KIF13A
LDLRAP1
MLH1
MSGN1
MTNR1B
MYG1
NECAP1
NTRK2
NUP54
PIP5K1C
POM121
PRKDC
PSORS1C2
RNF39
SHBG
SLC2A8
SMAD2
TBC1D22B
TSGA10IP
U2AF1
U2AF1L5
Entrez ID
53371
162
HPRD ID
06352
02541
Ensembl ID
ENSG00000138750
ENSG00000100280
Uniprot IDs
Q7Z3B4
Q10567
PDB IDs
4JNU
4JNV
4JO7
4JO9
5IJN
5IJO
4HMY
4P6Z
6CM9
6CRI
6D83
6D84
6DFF
Enriched GO Terms of Interacting Partners
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