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NUP54 and DCTN3
Data Source:
BioGRID
(two hybrid)
NUP54
DCTN3
Description
nucleoporin 54
dynactin subunit 3
Image
No pdb structure
GO Annotations
Cellular Component
Nuclear Envelope
Nuclear Membrane
Host Cell
Nuclear Pore Central Transport Channel
Condensed Chromosome Kinetochore
Nucleolus
Centrosome
Spindle
Cytosol
Dynactin Complex
Microtubule
Midbody
Cleavage Furrow
Perinuclear Region Of Cytoplasm
Molecular Function
Protein Binding
Structural Constituent Of Nuclear Pore
Identical Protein Binding
Protein-containing Complex Binding
Structural Molecule Activity
Protein Binding
Biological Process
Regulation Of Glycolytic Process
MRNA Export From Nucleus
TRNA Export From Nucleus
Protein Targeting
NLS-bearing Protein Import Into Nucleus
Nuclear Pore Organization
Viral Process
Protein Sumoylation
Viral Transcription
Protein Localization To Nuclear Inner Membrane
Regulation Of Protein Import Into Nucleus
Regulation Of Gene Silencing By MiRNA
Intracellular Transport Of Virus
Regulation Of Cellular Response To Heat
G2/M Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Microtubule-based Process
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Cytoskeleton-dependent Cytokinesis
Ciliary Basal Body-plasma Membrane Docking
Pathways
ISG15 antiviral mechanism
Transport of the SLBP independent Mature mRNA
Transport of the SLBP Dependant Mature mRNA
Transport of Mature mRNA Derived from an Intronless Transcript
Transport of Mature mRNA derived from an Intron-Containing Transcript
Rev-mediated nuclear export of HIV RNA
Transport of Ribonucleoproteins into the Host Nucleus
NS1 Mediated Effects on Host Pathways
Viral Messenger RNA Synthesis
NEP/NS2 Interacts with the Cellular Export Machinery
Regulation of Glucokinase by Glucokinase Regulatory Protein
Nuclear import of Rev protein
Vpr-mediated nuclear import of PICs
snRNP Assembly
SUMOylation of DNA damage response and repair proteins
SUMOylation of ubiquitinylation proteins
Nuclear Pore Complex (NPC) Disassembly
Regulation of HSF1-mediated heat shock response
SUMOylation of SUMOylation proteins
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA replication proteins
SUMOylation of DNA replication proteins
Transcriptional regulation by small RNAs
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)
tRNA processing in the nucleus
HCMV Early Events
HCMV Late Events
Postmitotic nuclear pore complex (NPC) reformation
MHC class II antigen presentation
Regulation of PLK1 Activity at G2/M Transition
HSP90 chaperone cycle for steroid hormone receptors (SHR)
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
COPI-mediated anterograde transport
COPI-independent Golgi-to-ER retrograde traffic
AURKA Activation by TPX2
Drugs
Diseases
GWAS
Hippocampal volume (
29274321
)
Interacting Genes
46 interacting genes:
AGR2
AP1B1
AP2B1
APC
BPIFA1
C14orf119
C1orf109
C21orf91
CCDC85B
CCHCR1
CDC23
CENPH
DCTN3
DGCR6
EFHC1
EIF3F
EXOC1
EXOC8
HAUS1
HAUS8
HGS
HOMER1
IFT20
KPNA1
KPNB1
KRT15
KRT27
KRT33B
NFKBID
NR3C1
NUP62
NUTF2
OIP5
PKNOX2
SMYD3
SOHLH1
SPG21
SSR1
TACC3
TCHP
TEKT1
TEX12
TPM3
TRIM54
VPS37C
ZWINT
11 interacting genes:
ATXN1
DCTN1
GSK3B
KRT34
NUP54
PBX2
PITX1
TRIM55
TRIP13
USHBP1
VPS37C
Entrez ID
53371
11258
HPRD ID
06352
06303
Ensembl ID
ENSG00000138750
ENSG00000137100
Uniprot IDs
Q7Z3B4
O75935
X6RLR1
PDB IDs
4JNU
4JNV
4JO7
4JO9
5IJN
5IJO
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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