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PFN2 and EVL
Data Source:
HPRD
(in vitro)
PFN2
EVL
Description
profilin 2
Enah/Vasp-like
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Cytoskeleton
Extracellular Exosome
Cytoplasm
Cytosol
Cytoskeleton
Focal Adhesion
Membrane
Lamellipodium
Molecular Function
Actin Binding
Actin Monomer Binding
Protein Binding
Phosphatidylinositol-4,5-bisphosphate Binding
ATPase Activity
Actin Binding
Protein Binding
Profilin Binding
SH3 Domain Binding
Biological Process
Negative Regulation Of Epithelial Cell Migration
Actin Cytoskeleton Organization
Regulation Of Actin Filament Polymerization
Negative Regulation Of Actin Filament Polymerization
Positive Regulation Of Actin Filament Polymerization
Positive Regulation Of Actin Filament Bundle Assembly
Positive Regulation Of ATPase Activity
Positive Regulation Of Peptidyl-serine Phosphorylation
Protein Stabilization
Positive Regulation Of Stress Fiber Assembly
Negative Regulation Of Ruffle Assembly
Actin Filament Organization
Cell Surface Receptor Signaling Pathway
Nervous System Development
Axon Guidance
Actin Polymerization Or Depolymerization
Animal Organ Morphogenesis
Negative Regulation Of Epithelial Cell Migration
Positive Regulation Of Actin Filament Polymerization
Actin Nucleation
Protein Homotetramerization
Positive Regulation Of Stress Fiber Assembly
Negative Regulation Of Ruffle Assembly
Pathways
Signaling by ROBO receptors
RHO GTPases Activate Formins
RHO GTPases Activate Formins
Generation of second messenger molecules
Signaling by ROBO receptors
Signaling by ROBO receptors
RHO GTPases Activate Formins
Drugs
Triglyme
Pentaglyme
Diseases
GWAS
Fish- and plant-related diet (
32066663
)
Blood protein levels (
30072576
)
White matter hyperintensities (
32358547
)
White matter hyperintensity burden (
25663218
)
Interacting Genes
34 interacting genes:
ACTB
ACTG1
ANTKMT
BIRC2
CCDC113
DDX11
DLST
DNM1
EEF1A1
ERCC6
EVL
FHOD1
FLT3LG
FMNL1
GOLGB1
HTT
IK
IVNS1ABP
MSANTD3
MYPOP
NDUFB8
PLAUR
PTPRS
RAP1GAP
RNF146
ROCK1
RPS10
SEPTIN5
SGTA
SNTA1
SYN1
TERF1
VASP
WDR33
33 interacting genes:
ABI1
ABI3
ABL1
APBB1
APBB1IP
CRKL
DNMBP
ENAH
FYB1
FYN
HCK
HTT
LYN
PFN2
POT1
PRPF40A
RAD51
SEMA6A
SH3RF1
SPTA1
SPTAN1
SRC
TCERG1
TERF1
TES
TRIM9
VASP
WAS
WASL
XIRP1
ZDHHC17
ZNF655
ZYX
Entrez ID
5217
51466
HPRD ID
01451
10942
Ensembl ID
ENSG00000070087
ENSG00000196405
Uniprot IDs
P35080
A0A024R6K5
Q9UI08
PDB IDs
1D1J
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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