Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
PFN2 and SYN1
Data Source:
HPRD
(in vitro)
PFN2
SYN1
Description
profilin 2
synapsin I
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Cytoskeleton
Extracellular Exosome
Synaptonemal Complex
Golgi Apparatus
Cytosol
Cytoskeleton
Synaptic Vesicle
Postsynaptic Density
Axon
Dendrite
Synaptic Vesicle Membrane
Presynaptic Active Zone
Schaffer Collateral - CA1 Synapse
Extrinsic Component Of Synaptic Vesicle Membrane
Anchored Component Of Synaptic Vesicle Membrane
Molecular Function
Actin Binding
Actin Monomer Binding
Protein Binding
Phosphatidylinositol-4,5-bisphosphate Binding
ATPase Activity
Actin Binding
Transporter Activity
Protein Binding
ATP Binding
Protein Kinase Binding
Identical Protein Binding
Calcium-dependent Protein Binding
Biological Process
Negative Regulation Of Epithelial Cell Migration
Actin Cytoskeleton Organization
Regulation Of Actin Filament Polymerization
Negative Regulation Of Actin Filament Polymerization
Positive Regulation Of Actin Filament Polymerization
Positive Regulation Of Actin Filament Bundle Assembly
Positive Regulation Of ATPase Activity
Positive Regulation Of Peptidyl-serine Phosphorylation
Protein Stabilization
Positive Regulation Of Stress Fiber Assembly
Negative Regulation Of Ruffle Assembly
Chemical Synaptic Transmission
Neurotransmitter Secretion
Regulation Of Neurotransmitter Secretion
Neuron Development
Synapse Organization
Synaptic Vesicle Clustering
Regulation Of Synaptic Vesicle Cycle
Regulation Of Synaptic Vesicle Exocytosis
Pathways
Signaling by ROBO receptors
RHO GTPases Activate Formins
RHO GTPases Activate Formins
Serotonin Neurotransmitter Release Cycle
Dopamine Neurotransmitter Release Cycle
Drugs
Triglyme
Pentaglyme
Adenosine 5'-[gamma-thio]triphosphate
Diseases
Syndromic X-linked mental retardation with epilepsy or seizures, including: West syndrome (WS); Partington syndrome (PRTS); Proud syndrome (ACCAG); XMR and epilepsy (XMRE); MRXHF1; XMR OPHN1-related (MRXSO) ; XELBD; XMR, Christianson type (MRXSC); Creatine deficiency syndrome (XL-CDS); Renpenning syndrome (RENS1); Epilepsy and mental retardation limited to females (EFMR); Periventricular nodular heterotopia (PVNH); Hydrocephalus (XLH); XMR, JARID1C related (MRXSJ); Boerjeson-Forssman syndrome (BFLS); CK syndrome (CKS)
GWAS
Fish- and plant-related diet (
32066663
)
Interacting Genes
34 interacting genes:
ACTB
ACTG1
ANTKMT
BIRC2
CCDC113
DDX11
DLST
DNM1
EEF1A1
ERCC6
EVL
FHOD1
FLT3LG
FMNL1
GOLGB1
HTT
IK
IVNS1ABP
MSANTD3
MYPOP
NDUFB8
PLAUR
PTPRS
RAP1GAP
RNF146
ROCK1
RPS10
SEPTIN5
SGTA
SNTA1
SYN1
TERF1
VASP
WDR33
30 interacting genes:
AMPH
BIN1
BLM
CAMK1
CAMK2G
CDK5
CRK
ERG
GRB2
ITSN2
KAT5
MAPK3
NOS1
NOS1AP
PAK1
PAK2
PAK3
PFN2
PIK3R1
PLCG1
PRKACA
RASA1
RB1CC1
S100A1
SNCA
SPTAN1
SRC
SYN2
SYN3
VIM
Entrez ID
5217
6853
HPRD ID
01451
02433
Ensembl ID
ENSG00000070087
ENSG00000008056
Uniprot IDs
P35080
P17600
PDB IDs
1D1J
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?