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POLR3K and CENPP
Data Source:
BioGRID
(two hybrid)
POLR3K
CENPP
Description
RNA polymerase III subunit K
centromere protein P
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
RNA Polymerase III Complex
Nucleolus
Cytosol
Chromosome, Centromeric Region
Nucleus
Nucleoplasm
Nucleolus
Cytosol
Molecular Function
Nucleic Acid Binding
DNA-directed 5'-3' RNA Polymerase Activity
Protein Binding
Zinc Ion Binding
Protein Binding
Biological Process
Transcription By RNA Polymerase III
Termination Of RNA Polymerase III Transcription
Positive Regulation Of Type I Interferon Production
TRNA 3'-trailer Cleavage
Innate Immune Response
Defense Response To Virus
CENP-A Containing Nucleosome Assembly
Pathways
Cytosolic sensors of pathogen-associated DNA
RNA Polymerase III Chain Elongation
RNA Polymerase III Transcription Termination
RNA Polymerase III Abortive And Retractive Initiation
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Deposition of new CENPA-containing nucleosomes at the centromere
Mitotic Prometaphase
EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
Body mass index (
26426971
)
Mean corpuscular volume (
32888494
)
Red blood cell traits (
23446634
)
Blood protein levels (
29875488
)
End-stage renal disease (
29885931
)
HDL cholesterol levels (
32203549
)
Height (
28552196
31562340
)
Malaria (
31844061
)
Pulse pressure (
30578418
)
Systolic blood pressure (
30224653
30578418
)
Triglyceride levels (
32203549
)
Urate levels (
31578528
)
Interacting Genes
3 interacting genes:
CENPP
SDCBP
TRIM69
27 interacting genes:
ATP6V0D2
BACH2
C2orf88
CCDC33
CCDC85B
CENPO
CEP44
GOLGA2
HAUS1
KIAA1328
KLC3
LMNA
MBD3
NHLH1
NTAQ1
PKNOX2
POLR3K
RNF126
RPIA
SERTAD3
STXBP1
SYCE1L
TEX11
TOX2
USHBP1
ZNF341
ZNF765
Entrez ID
51728
401541
HPRD ID
16187
17989
Ensembl ID
ENSG00000161980
ENSG00000188312
Uniprot IDs
Q9Y2Y1
Q6IPU0
Q7Z672
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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