PDCD2 and NFKBIB

Data Source:
HPRD (in vitro)

		PDCD2	NFKBIB
Description		programmed cell death 2	NFKB inhibitor beta
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Extracellular Exosome	Nucleus Cytosol
	Molecular Function	DNA Binding Protein Binding Enzyme Binding Metal Ion Binding	Transcription Coactivator Activity Protein Binding
	Biological Process	Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Apoptotic Process Regulation Of Hematopoietic Progenitor Cell Differentiation Positive Regulation Of Hematopoietic Stem Cell Proliferation	Transcription, DNA-templated Signal Transduction Cytoplasmic Sequestering Of NF-kappaB Positive Regulation Of Transcription, DNA-templated Cellular Response To Lipopolysaccharide
Pathways			Activation of NF-kappaB in B cells RIP-mediated NFkB activation via ZBP1 TAK1 activates NFkB by phosphorylation and activation of IKKs complex TRAF6 mediated NF-kB activation
Drugs
Diseases
GWAS		Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653)
Interacting Genes		7 interacting genes: ERRFI1 HCFC1 LSM8 NCOR1 NFKBIB PRKN TBC1D21	43 interacting genes: APP BAK1 BTBD6 BTRC CDC25A CHUK CSNK2A1 CUL1 DNAJA3 ESR2 FHL3 GIT2 IKBKB IKBKG KPNA2 LRPPRC MCC MTIF2 NCOR2 NDUFB7 NFKB1 NFKB2 NFKBIA NGFR NKIRAS1 NKIRAS2 PDCD2 POLR1A POLR1B POLR1C POLR1D POLR1E POLR1G POLR2H POLR2L PPARG RASAL2 REL RELA RXRA SKP1 TSPAN1 VPS52
Entrez ID		5134	4793
HPRD ID		02922	07260
Ensembl ID		ENSG00000071994	ENSG00000104825
Uniprot IDs		A0A087WYJ3 Q16342	G5E9C2 Q15653
PDB IDs
Enriched GO Terms of Interacting Partners?
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