PLSCR4 and CLPP

Data Source:
BioGRID (two hybrid)

		PLSCR4	CLPP
Description		phospholipid scramblase 4	caseinolytic mitochondrial matrix peptidase proteolytic subunit
Image
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Mitochondrion Mitochondrial Matrix Endopeptidase Clp Complex
	Molecular Function	Calcium Ion Binding Protein Binding SH3 Domain Binding Phospholipid Scramblase Activity Enzyme Binding CD4 Receptor Binding	Endopeptidase Activity ATP-dependent Peptidase Activity Serine-type Endopeptidase Activity Protein Binding Peptidase Activity Identical Protein Binding ATPase Binding
	Biological Process	Plasma Membrane Phospholipid Scrambling Cellular Response To Lipopolysaccharide	Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Membrane Protein Proteolysis Proteolysis Involved In Cellular Protein Catabolic Process
Pathways
Drugs			N-Formylmethionine
Diseases
GWAS		Lymphocyte counts ( 32888494) Monocyte count ( 32888494)
Interacting Genes		62 interacting genes: ABHD17A ADAMTSL4 APLN ATP23 C11orf1 CES1 CLPP CRCT1 DAZAP2 DDIT4L EFEMP2 FCHO1 GATA1 HDHD3 HOXA1 INTS11 ITGB4 KLHL38 KPRP KRT82 KRTAP1-5 KRTAP10-8 KRTAP19-1 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP21-2 KRTAP3-1 KRTAP3-3 KRTAP4-12 KRTAP4-2 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP8-1 LCE1A LCE1C LCE2B LCE5A LPXN MTUS2 NID2 NOTCH2NLA OXER1 PCSK5 PLSCR1 RAMAC RBP3 RBPMS RPS27A SLC15A2 SSC4D TEKT5 TENM4 TRIM42 TRIP13 TSPAN4 UBA52 UBB UBC YPEL3 ZNF34	16 interacting genes: ABI2 C14orf119 CLPX DTX2 EFEMP1 EFEMP2 GRN KRTAP10-1 NUTF2 P4HA3 PLSCR4 PPP2CA PSMB1 RBPMS TNPO3 TRIM54
Entrez ID		57088	8192
HPRD ID		07401	03074
Ensembl ID		ENSG00000114698	ENSG00000125656
Uniprot IDs		E9PHR9 Q9NRQ2	Q16740
PDB IDs		3Q5U	1TG6 6BBA 6DL7 6H23
Enriched GO Terms of Interacting Partners?
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