DESI2 and SPART

		DESI2	SPART
Description		desumoylating isopeptidase 2	spartin
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Cytoplasm Mitochondrial Outer Membrane Lipid Droplet Cytosol Plasma Membrane Midbody Synapse
	Molecular Function	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Lys63-specific Deubiquitinase Activity Ubiquitinyl Hydrolase Activity Lys48-specific Deubiquitinase Activity	Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	Protein Deubiquitination Protein Phosphopantetheinylation Protein K63-linked Deubiquitination Protein Modification By Small Protein Removal Protein K48-linked Deubiquitination	Abscission Negative Regulation Of BMP Signaling Pathway Lipid Droplet Organization Negative Regulation Of Collateral Sprouting In Absence Of Injury Neuromuscular Process Cell Division Regulation Of Mitochondrial Membrane Potential Adipose Tissue Development
Pathways
Drugs
Diseases			Hereditary spastic paraplegia (SPG)
GWAS
Interacting Genes		11 interacting genes: ARFIP1 BNIP2 COQ8A MYG1 NFU1 PBX3 PLIN2 SEMA3G SH3GLB1 SPART THAP7	22 interacting genes: APP APPL1 DESI2 EPN2 EPS15 GPR35 ITCH MAP3K1 OTUB2 OTUD7B OTULIN PLIN3 PRKAR1A RABGEF1 SMURF1 SMURF2 TUBA1A UBAC1 USP5 WWP2 YOD1 ZFYVE9
Entrez ID		51029	23111
HPRD ID		15153	06170
Ensembl ID		ENSG00000121644	ENSG00000133104
Uniprot IDs		A0A024R5P6 A0A024R5P9 Q9BSY9	A0A024RDV9 Q8N0X7
PDB IDs			2DL1 4U7I
Enriched GO Terms of Interacting Partners?
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