DESI2 and PBX3

Data Source:
BioGRID (two hybrid)

		DESI2	PBX3
Description		desumoylating isopeptidase 2	PBX homeobox 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Chromatin Nucleus
	Molecular Function	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Lys63-specific Deubiquitinase Activity Ubiquitinyl Hydrolase Activity Lys48-specific Deubiquitinase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
	Biological Process	Protein Deubiquitination Protein Phosphopantetheinylation Protein K63-linked Deubiquitination Protein Modification By Small Protein Removal Protein K48-linked Deubiquitination	Eye Development Regulation Of Transcription By RNA Polymerase II Anterior Compartment Pattern Formation Posterior Compartment Specification Brain Development Animal Organ Morphogenesis Embryonic Organ Development Neuron Development
Pathways
Drugs
Diseases
GWAS			Dentures ( 31235808) Fish- and plant-related diet ( 32066663) Medication use (opioids) ( 31015401) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Pulse pressure ( 30578418) Raw vegetable consumption ( 32066663) Refractive error ( 32231278) Response to mTOR inhibitor (everolimus) ( 24009623) Sleep duration ( 30531941) Squamous cell lung carcinoma ( 28604730) Systolic blood pressure ( 30224653 30578418)
Interacting Genes		11 interacting genes: ARFIP1 BNIP2 COQ8A MYG1 NFU1 PBX3 PLIN2 SEMA3G SH3GLB1 SPART THAP7	63 interacting genes: AGTRAP ARFIP2 ARL6IP1 BIK BSND CAV3 CIDEB CMTM4 CMTM5 COQ8A CPLX2 DESI2 DGAT2L6 FADS6 FAM177A1 FKBP7 FSD2 GAD2 GBP7 HIGD1C HOXA9 HOXB8 HSD17B13 INPP5K INSYN1 ITGB3BP KRT27 KRT31 LIME1 MAGEA1 MAGEC2 MAL2 MBLAC2 MDK MEIS1 MICOS13 MTERF3 NUDT9 PLIN3 PRB3 PTPN9 RABAC1 REEP5 RHBDD2 RHEX RNF186 RPRM SCAMP1 SFT2D2 SIN3A SMPD2 SYP SYPL1 TFIP11 TMCO2 TMEM196 TPD52L1 TPM3 TRAF1 TRIM44 TVP23B ZNF655 ZNHIT3
Entrez ID		51029	5090
HPRD ID		15153	15938
Ensembl ID		ENSG00000121644	ENSG00000167081
Uniprot IDs		A0A024R5P6 A0A024R5P9 Q9BSY9	P40426 Q5JS98 Q96AL5
PDB IDs
Enriched GO Terms of Interacting Partners?
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