DESI2 and COQ8A

		DESI2	COQ8A
Description		desumoylating isopeptidase 2	coenzyme Q8A
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Mitochondrion Integral Component Of Membrane Extrinsic Component Of Mitochondrial Inner Membrane
	Molecular Function	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Lys63-specific Deubiquitinase Activity Ubiquitinyl Hydrolase Activity Lys48-specific Deubiquitinase Activity	Protein Kinase Activity Protein Binding ATP Binding Kinase Activity ADP Binding
	Biological Process	Protein Deubiquitination Protein Phosphopantetheinylation Protein K63-linked Deubiquitination Protein Modification By Small Protein Removal Protein K48-linked Deubiquitination	Protein Phosphorylation Ubiquinone Biosynthetic Process Phosphorylation
Pathways
Drugs			Fostamatinib
Diseases			Coenzyme Q10 deficiency Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS
Interacting Genes		11 interacting genes: ARFIP1 BNIP2 COQ8A MYG1 NFU1 PBX3 PLIN2 SEMA3G SH3GLB1 SPART THAP7	26 interacting genes: ABHD5 AGTRAP CCDC34 CMTM4 CMTM5 CMTM6 COQ9 DESI2 DTX2 JOSD2 MAL2 MRM1 MTIF3 ORMDL3 PBX3 RABAC1 REEP6 RPRM SH3GLB1 SMPD2 STX10 TFIP11 TMCO2 TMEM159 TMEM239 TPD52L2
Entrez ID		51029	56997
HPRD ID		15153	07375
Ensembl ID		ENSG00000121644	ENSG00000163050
Uniprot IDs		A0A024R5P6 A0A024R5P9 Q9BSY9	Q8NI60
PDB IDs			4PED 5I35
Enriched GO Terms of Interacting Partners?
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