OTX1 and KRTAP3-2

Data Source:
BioGRID (two hybrid, two hybrid)

		OTX1	KRTAP3-2
Description		orthodenticle homeobox 1	keratin associated protein 3-2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Cytosol Keratin Filament
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding	Structural Molecule Activity Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Anterior/posterior Pattern Specification Metencephalon Development Midbrain Development Inner Ear Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Diencephalon Morphogenesis	Keratinization
Pathways			Keratinization
Drugs
Diseases
GWAS		Fruit consumption ( 32066663) Neurociticism ( 29500382) Regular attendance at a religious group ( 29970889) Risk-taking tendency (4-domain principal component model) ( 30643258)
Interacting Genes		144 interacting genes: ADAM12 ADAMTSL4 ALPP ANKRD10 ARHGEF17 ARID5A ATG9B BHLHB9 C10orf55 C11orf1 CCN4 CERCAM CH25H CHIC2 CHRD CHRDL2 COL8A1 COMP CTAG2 CYSRT1 DPY30 EFEMP2 ETFDH FAM168B FAM72B FBLN2 FBLN5 FHL5 GEMIN8P4 GPRIN2 GRN HIVEP1 INTS11 KCNK16 KLHL26 KPRP KRT31 KRT35 KRT37 KRT81 KRT85 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP12-4 KRTAP13-1 KRTAP13-2 KRTAP13-3 KRTAP17-1 KRTAP19-2 KRTAP19-7 KRTAP2-3 KRTAP2-4 KRTAP22-1 KRTAP26-1 KRTAP3-1 KRTAP3-2 KRTAP3-3 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP4-7 KRTAP5-11 KRTAP5-3 KRTAP5-6 KRTAP5-9 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP7-1 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LASP1 LCE1B LCE1C LCE1F LCE2A LCE2B LCE2C LCE2D LCE4A LGALS13 M1AP MDFI MGAT5B MIIP MTNR1B NBPF19 NDUFAF6 NECTIN3 NHLRC4 NOTCH2NLA OXER1 PCSK5 PLA2G10 PLEKHG4 PLSCR2 POU2AF1 PRICKLE4 PRR13 PRR22 RBPMS RGS17 RGS19 RGS20 RNF144B RTN4R SLC15A2 SMARCC1 SPRY1 SPRY2 SPRY4 SPRYD7 TEX37 TLE4 TNS2 TRIM42 TRIP6 TSPAN4 UBAP2 USP54 VWC2 VWC2L WWOX YPEL3 ZBTB42 ZNF330 ZNF34	75 interacting genes: ADAM12 ADAMTSL3 AQP1 ARFGAP1 ATG9A C5orf60 CATSPER1 CCDC28A-AS1 CELF5 CERK CNNM3 COL8A1 CREB5 DHRS1 DUSP10 EFEMP2 FAM71C FOXD2 FRS3 GAD1 GATA1 GUCD1 HOXA1 HOXB9 HYAL2 HYPK ITGB5 KIF25-AS1 KPRP KRTAP10-1 KRTAP10-5 KRTAP10-8 KRTAP12-1 KRTAP12-2 KRTAP13-3 KRTAP15-1 KRTAP26-1 KRTAP4-12 KRTAP4-4 KRTAP9-2 KRTAP9-3 LASP1 LCE1A LCE1B LCE1F LCE2A LCE3A LCE3C LCE3D LCE3E LCE4A MAN2B2 MAPKBP1 NR1D2 NTM NUFIP2 OLIG3 OTX1 PCSK5 PLSCR3 POGZ POU4F2 PPP1R32 PRR34 R3HDM2 SLC13A5 SMARCC1 SPRY1 TBC1D16 TRIM42 TRIP13 VASN YIPF3 ZIC1 ZIM2
Entrez ID		5013	83897
HPRD ID		08964	13938
Ensembl ID		ENSG00000115507	ENSG00000212900
Uniprot IDs		P32242	Q9BYR7
PDB IDs
Enriched GO Terms of Interacting Partners?
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