OTX1 and KRTAP26-1

Data Source:
BioGRID (two hybrid)

		OTX1	KRTAP26-1
Description		orthodenticle homeobox 1	keratin associated protein 26-1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Cytosol Intermediate Filament
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Anterior/posterior Pattern Specification Metencephalon Development Midbrain Development Inner Ear Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Diencephalon Morphogenesis	Keratinization
Pathways			Keratinization
Drugs
Diseases
GWAS		Fruit consumption ( 32066663) Neurociticism ( 29500382) Regular attendance at a religious group ( 29970889) Risk-taking tendency (4-domain principal component model) ( 30643258)
Interacting Genes		144 interacting genes: ADAM12 ADAMTSL4 ALPP ANKRD10 ARHGEF17 ARID5A ATG9B BHLHB9 C10orf55 C11orf1 CCN4 CERCAM CH25H CHIC2 CHRD CHRDL2 COL8A1 COMP CTAG2 CYSRT1 DPY30 EFEMP2 ETFDH FAM168B FAM72B FBLN2 FBLN5 FHL5 GEMIN8P4 GPRIN2 GRN HIVEP1 INTS11 KCNK16 KLHL26 KPRP KRT31 KRT35 KRT37 KRT81 KRT85 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP12-4 KRTAP13-1 KRTAP13-2 KRTAP13-3 KRTAP17-1 KRTAP19-2 KRTAP19-7 KRTAP2-3 KRTAP2-4 KRTAP22-1 KRTAP26-1 KRTAP3-1 KRTAP3-2 KRTAP3-3 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP4-7 KRTAP5-11 KRTAP5-3 KRTAP5-6 KRTAP5-9 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP7-1 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LASP1 LCE1B LCE1C LCE1F LCE2A LCE2B LCE2C LCE2D LCE4A LGALS13 M1AP MDFI MGAT5B MIIP MTNR1B NBPF19 NDUFAF6 NECTIN3 NHLRC4 NOTCH2NLA OXER1 PCSK5 PLA2G10 PLEKHG4 PLSCR2 POU2AF1 PRICKLE4 PRR13 PRR22 RBPMS RGS17 RGS19 RGS20 RNF144B RTN4R SLC15A2 SMARCC1 SPRY1 SPRY2 SPRY4 SPRYD7 TEX37 TLE4 TNS2 TRIM42 TRIP6 TSPAN4 UBAP2 USP54 VWC2 VWC2L WWOX YPEL3 ZBTB42 ZNF330 ZNF34	91 interacting genes: ACY3 ARID5A C19orf54 CARD10 CCNJL CELF5 CERCAM CFAP206 COL8A1 CYSRT1 DAZAP2 DTX2 EFEMP2 FAM168B FAM222B GDPD5 GRN HGS HNF1B HOXA1 ID3 INTS11 KRT34 KRTAP1-1 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP13-2 KRTAP19-6 KRTAP19-7 KRTAP21-2 KRTAP3-1 KRTAP3-2 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-7 KRTAP5-6 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP8-1 KRTAP9-2 KRTAP9-8 LASP1 LCE2B MAPKBP1 MGAT5B NBPF19 NHLRC4 NOTCH2NLA OTX1 PITX1 PLA2G10 PM20D2 PRR22 PRR35 PSMA3 RASD1 RBPMS RECK RHOXF2 RNF208 SF1 SIVA1 SLC15A2 SMARCC1 SMUG1 SPAG8 SPATA12 SSC4D STK16 TEKT3 TEKT4 TENT5A TEX37 TFAP2D TFG TOX TRIM42 TRIP13 TRIP6 VASN VENTX YTHDF1 ZNF34
Entrez ID		5013	388818
HPRD ID		08964	14206
Ensembl ID		ENSG00000115507	ENSG00000197683
Uniprot IDs		P32242	Q6PEX3
PDB IDs
Enriched GO Terms of Interacting Partners?
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