OTX1 and BHLHB9

Data Source:
BioGRID (two hybrid)

		OTX1	BHLHB9
Description		orthodenticle homeobox 1	basic helix-loop-helix family member b9
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleoplasm Cytosol Extracellular Exosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Protein Homodimerization Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Anterior/posterior Pattern Specification Metencephalon Development Midbrain Development Inner Ear Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Diencephalon Morphogenesis	Learning Or Memory Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Neurogenesis Positive Regulation Of Synapse Assembly Positive Regulation Of Dendritic Spine Morphogenesis
Pathways
Drugs
Diseases
GWAS		Fruit consumption ( 32066663) Neurociticism ( 29500382) Regular attendance at a religious group ( 29970889) Risk-taking tendency (4-domain principal component model) ( 30643258)
Interacting Genes		144 interacting genes: ADAM12 ADAMTSL4 ALPP ANKRD10 ARHGEF17 ARID5A ATG9B BHLHB9 C10orf55 C11orf1 CCN4 CERCAM CH25H CHIC2 CHRD CHRDL2 COL8A1 COMP CTAG2 CYSRT1 DPY30 EFEMP2 ETFDH FAM168B FAM72B FBLN2 FBLN5 FHL5 GEMIN8P4 GPRIN2 GRN HIVEP1 INTS11 KCNK16 KLHL26 KPRP KRT31 KRT35 KRT37 KRT81 KRT85 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP12-4 KRTAP13-1 KRTAP13-2 KRTAP13-3 KRTAP17-1 KRTAP19-2 KRTAP19-7 KRTAP2-3 KRTAP2-4 KRTAP22-1 KRTAP26-1 KRTAP3-1 KRTAP3-2 KRTAP3-3 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP4-7 KRTAP5-11 KRTAP5-3 KRTAP5-6 KRTAP5-9 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP7-1 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LASP1 LCE1B LCE1C LCE1F LCE2A LCE2B LCE2C LCE2D LCE4A LGALS13 M1AP MDFI MGAT5B MIIP MTNR1B NBPF19 NDUFAF6 NECTIN3 NHLRC4 NOTCH2NLA OXER1 PCSK5 PLA2G10 PLEKHG4 PLSCR2 POU2AF1 PRICKLE4 PRR13 PRR22 RBPMS RGS17 RGS19 RGS20 RNF144B RTN4R SLC15A2 SMARCC1 SPRY1 SPRY2 SPRY4 SPRYD7 TEX37 TLE4 TNS2 TRIM42 TRIP6 TSPAN4 UBAP2 USP54 VWC2 VWC2L WWOX YPEL3 ZBTB42 ZNF330 ZNF34	59 interacting genes: ANKRD11 APP AQP1 BEX2 C2CD6 CCDC120 CDC23 CDC37 CDCA7L CT55 DDX6 EAF1 EIF3B ENKD1 FAM124B FAM161A FAM214B FAM90A1 GAS8 GEM GPANK1 HOXA1 INO80B IPO5 IQUB KLHL38 L3MBTL2 LEO1 LMO1 LONRF1 MFAP1 MISP MPP1 MYO15B NRIP1 OTX1 PALS1 PHF1 PNMA5 POLR1C PPP2R5E PRKAB2 PRPF31 RCOR3 SCNM1 SH3KBP1 SMARCD1 SPANXN2 TASOR2 TCEA2 TEPSIN THOC1 TLK1 TOP3B TSGA10IP TXN2 USP2 USP20 ZNF417
Entrez ID		5013	80823
HPRD ID		08964	10028
Ensembl ID		ENSG00000115507	ENSG00000198908
Uniprot IDs		P32242	Q6PI77
PDB IDs
Enriched GO Terms of Interacting Partners?
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