KRTAP3-2 and ADAMTSL3

Data Source:
BioGRID (two hybrid)

		KRTAP3-2	ADAMTSL3
Description		keratin associated protein 3-2	ADAMTS like 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Keratin Filament	Extracellular Matrix Intracellular Membrane-bounded Organelle
	Molecular Function	Structural Molecule Activity Protein Binding	Metalloendopeptidase Activity Protein Binding
	Biological Process	Keratinization	Proteolysis Extracellular Matrix Organization
Pathways		Keratinization	Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins
Drugs
Diseases
GWAS			Amyotrophic lateral sclerosis (sporadic) ( 24529757) Appendicular lean mass ( 28724990) Asthma ( 32296059) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder lithium response (categorical) or schizophrenia ( 29121268) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body size at age 10 ( 32376654) Childhood body mass index ( 33045005) Chronic obstructive pulmonary disease ( 30804561) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Height ( 21998595 28552196 20881960 25282103 25429064 19343178 23563607 31562340 18391950 18391951 18391952 20397748 20189936) Hip circumference ( 25673412) Hip circumference adjusted for BMI ( 28552196 25673412) Lean body mass ( 28724990) Optic disc size ( 31809533) Pulse pressure ( 30224653) Schizophrenia ( 28991256 25056061 29483656 30285260) Spine bone size ( 31053729) Waist circumference ( 26785701) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 28552196 26785701 25673412 28448500)
Interacting Genes		75 interacting genes: ADAM12 ADAMTSL3 AQP1 ARFGAP1 ATG9A C5orf60 CATSPER1 CCDC28A-AS1 CELF5 CERK CNNM3 COL8A1 CREB5 DHRS1 DUSP10 EFEMP2 FAM71C FOXD2 FRS3 GAD1 GATA1 GUCD1 HOXA1 HOXB9 HYAL2 HYPK ITGB5 KIF25-AS1 KPRP KRTAP10-1 KRTAP10-5 KRTAP10-8 KRTAP12-1 KRTAP12-2 KRTAP13-3 KRTAP15-1 KRTAP26-1 KRTAP4-12 KRTAP4-4 KRTAP9-2 KRTAP9-3 LASP1 LCE1A LCE1B LCE1F LCE2A LCE3A LCE3C LCE3D LCE3E LCE4A MAN2B2 MAPKBP1 NR1D2 NTM NUFIP2 OLIG3 OTX1 PCSK5 PLSCR3 POGZ POU4F2 PPP1R32 PRR34 R3HDM2 SLC13A5 SMARCC1 SPRY1 TBC1D16 TRIM42 TRIP13 VASN YIPF3 ZIC1 ZIM2	14 interacting genes: CYSRT1 GLRX3 KRT40 KRTAP1-1 KRTAP10-3 KRTAP10-6 KRTAP10-8 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP3-2 KRTAP5-7 MDFI NOTCH2NLA
Entrez ID		83897	57188
HPRD ID		13938	12426
Ensembl ID		ENSG00000212900	ENSG00000156218
Uniprot IDs		Q9BYR7	P82987
PDB IDs
Enriched GO Terms of Interacting Partners?
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