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BTBD6 and DAXX
Data Source:
BioGRID
(two hybrid)
BTBD6
DAXX
Description
BTB domain containing 6
death domain associated protein
Image
GO Annotations
Cellular Component
Cytosol
Chromosome, Centromeric Region
Nucleus
Nucleoplasm
Nucleolus
Cytosol
Nuclear Body
PML Body
Molecular Function
P53 Binding
Transcription Coactivator Activity
Transcription Corepressor Activity
Protein Binding
Transcription Factor Binding
Enzyme Binding
Protein Kinase Binding
Protein Kinase Activator Activity
Heat Shock Protein Binding
Ubiquitin Protein Ligase Binding
Histone Binding
Protein N-terminus Binding
Androgen Receptor Binding
Sumo-dependent Protein Binding
Transcription Regulator Inhibitor Activity
Biological Process
Neurogenesis
Post-translational Protein Modification
Positive Regulation Of Protein Phosphorylation
Nucleosome Assembly
Chromatin Remodeling
Regulation Of Transcription, DNA-templated
Activation Of JUN Kinase Activity
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Viral Process
Androgen Receptor Signaling Pathway
Regulation Of Protein Ubiquitination
Cellular Response To Heat
Cellular Response To Unfolded Protein
Regulation Of Apoptotic Process
Positive Regulation Of Protein Kinase Activity
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Cellular Response To Cadmium Ion
Cellular Response To Copper Ion
Cellular Response To Diamide
Positive Regulation Of Neuron Death
Cellular Response To Sodium Arsenite
Pathways
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation
SUMOylation of transcription cofactors
Regulation of TP53 Degradation
HCMV Early Events
Inhibition of DNA recombination at telomere
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations
Drugs
Diseases
GWAS
Adult body size (
32376654
)
Autism spectrum disorder or schizophrenia (
28540026
)
Disrupted circadian rhythm (low relative amplitude of rest-activity cycles) (
30120083
)
Lung cancer (
28604730
)
Lung cancer in ever smokers (
28604730
)
Interacting Genes
8 interacting genes:
BTBD3
CUL3
DAXX
NFKBIB
NME7
NTAQ1
PAXIP1
TCEA2
113 interacting genes:
ACVR2A
AIRE
AMOTL2
AR
ATM
ATRX
BTBD6
CA12
CALCOCO2
CARD9
CARM1
CBS
CDCA7L
CENPC
CEP63
CEP70
CFLAR
CREBBP
CSNK2A1
DAPK3
DKC1
DMAP1
DNMT1
ESRRG
ETS1
FAM9B
FANCA
FAS
FASLG
FTH1
GAS8
GOLGA2
GOLGA6L9
GRIPAP1
H3-3A
H3-3B
H3-5
H3C3
H4-16
H4C6
HABP4
HBA1
HDAC1
HDAC2
HDAC3
HIPK1
HIPK2
HIPK3
HSF1
HSF4
HSPB1
KCTD4
MAP3K5
MCRS1
MDM2
MEN1
MIPOL1
MKRN1
MSANTD4
MX1
MYH11
NECAB2
NSD3
PARK7
PAX3
PAX5
PBXIP1
PIBF1
PLAGL1
PML
PNMA1
PRMT1
PTEN
RASSF1
RASSF3
RIPK3
RNF4
RPL13
SENP2
SERBP1
SLC2A4
SLC9A1
SNW1
SPN
SQSTM1
SSX2IP
STAT3
STK4
STUB1
SUMO1
SUMO2
SUMO3
TAX1BP1
TCF3
TCF4
TCF7L2
TFIP11
TGFB1
TGFBR2
TNFRSF1A
TP53
TP63
TP73
TRAF3
TRIM21
TRIM54
TSG101
UBC
UBE2I
USH1G
USP7
ZBTB2
ZBTB26
Entrez ID
90135
1616
HPRD ID
12540
04424
Ensembl ID
ENSG00000184887
ENSG00000204209
Uniprot IDs
A0A384NYR4
Q96KE9
A0A024RCS3
B4E1C1
Q53F85
Q9UER7
PDB IDs
2VKP
2KQS
2KZS
2KZU
4H9N
4H9O
4H9P
4H9Q
4H9R
4H9S
4HGA
5GRQ
5KDM
5Y18
5Y6O
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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