Description |
ATM serine/threonine kinase |
DNA topoisomerase I |
Image |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
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- Accelerated cognitive decline after conversion of mild cognitive impairment to Alzheimer's disease (Alzhiemer's diagnosis trajectory interaction) ( 28560309)
- Antipsychotic drug-induced weight gain in schizophrenia ( 31447353)
- Brain morphology (MOSTest) ( 32665545)
- Cholesterol, total ( 24097068 20686565)
- Hemoglobin ( 32888494)
- LDL cholesterol ( 24097068 20686565)
- LDL cholesterol levels ( 28334899)
- LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535)
- LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
- Male-pattern baldness ( 28196072)
- Metabolite levels ( 23823483)
- PR interval ( 32439900)
- Red blood cell count ( 32888494)
- Refractive error ( 32231278)
- Total cholesterol levels ( 28334899)
- Urate levels ( 31578528)
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Interacting Genes |
98 interacting genes:
AATF
ABL1
ACTL6B
AP1B1
AP2B1
AP3B1
AP3B2
ATR
BCAS3
BCL10
BRCA1
BRCA2
CDC6
CDKN2C
CHD4
CHEK1
CHEK2
COPS5
CREB1
CRX
CSNK1D
CXXC5
DAXX
DCAF1
DCLRE1C
DDX1
DYRK2
E2F1
E4F1
EEF1E1
EIF3E
EIF4EBP1
ERRFI1
ESRRG
EXO1
FANCD2
FECH
FOXO3
H2AX
HIF1A
HSPA8
IL24
KAT5
KAT8
LIG4
MAP1S
MCM2
MCPH1
MDC1
MDM2
MDM4
MRE11
MT-ND4
MTA3
NBN
NR4A1
NREP
NSD3
OSGIN1
PARP1
PEX5
POLR2A
PPP2R5C
PRKDC
PTCH1
RAD17
RAD51
RAD9A
RANBP9
RASSF1
RBBP8
RHEB
RNF20
RNF40
RPA1
RPA2
SMC1A
SPSB1
STK11
TCL1A
TELO2
TERF1
TERF2
TFF1
TIPARP
TOP1
TOPBP1
TP53
TP53BP1
TRAF6
TREX1
TRIM29
UCHL3
WRN
XPA
XRCC5
ZEB1
ZNF821
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60 interacting genes:
APAF1
APP
ATM
BARD1
BRCA1
BRD2
BTBD1
BTBD2
BUB3
CASP3
CASP6
CDK8
CKAP5
CSNK2A1
CSNK2A2
DDB2
ELK3
ERCC8
ERG
FSHR
GEMIN4
IL7R
IRF4
IRF8
IRF9
JAK1
JUN
KMT2A
LIG4
LSM4
MDM2
NCL
NCOA6
PDE10A
PPP2R2B
PRB1
PRKDC
PYGM
RBL1
RBL2
RCVRN
SF3B1
SFPQ
SNRNP70
SNW1
SRPK2
SRSF1
SRSF11
SUMO1
SYMPK
TARBP2
TDP1
TOPORS
TP53
TRIM32
TUBD1
U2AF2
UBE2I
XRCC5
XRCC6
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Entrez ID |
472 |
7150 |
HPRD ID |
06347 |
00535 |
Ensembl ID |
ENSG00000149311
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ENSG00000198900
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Uniprot IDs |
A0A024R3C7
Q13315
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P11387
Q9BVT2
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PDB IDs |
5NP0
5NP1
6HKA
6K9K
6K9L
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1A31
1A35
1A36
1EJ9
1K4S
1K4T
1LPQ
1NH3
1R49
1RR8
1RRJ
1SC7
1SEU
1T8I
1TL8
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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